Evidence map›Paper›PMID 38545179›Full record

ArticleHeliyon2024

Fungal metabolite 6-pentyl-α-pyrone reduces canine coronavirus infection.

Claudia Cerracchio, Luca Del Sorbo, Francesco Serra, Alessia Staropoli, Maria Grazia Amoroso, Francesco Vinale, Filomena Fiorito

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Claudia CerracchioDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.
Luca Del SorboDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.
Francesco SerraDepartment of Animal Health, Unit of Virology, Istituto Zooprofilattico del Mezzogiorno, Portici, 80055 Naples, Italy.
Alessia StaropoliDepartment of Agricultural Sciences, University of Naples Federico II, Portici, Naples, Italy.
Maria Grazia AmorosoDepartment of Animal Health, Unit of Virology, Istituto Zooprofilattico del Mezzogiorno, Portici, 80055 Naples, Italy.
Francesco VinaleDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.
Filomena FioritoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.
University of Naples Federico II · ITIstituto Zooprofilattico Sperimentale del Mezzogiorno · ITInstitute for Sustainable Plant Protection · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine coronavirus (CCoV) can produce a self-limited enteric disease in dogs but, because of notable biological plasticity of coronaviruses (CoVs), numerous mutations as well as recombination events happen leading to the emergence of variants often more dangerous for both animals and humans. Indeed, the emergence of new canine-feline recombinant alphacoronaviruses, recently isolated from humans, highlight the cross-species transmission potential of CoVs. Consequently, new effective antiviral agents are required to treat CoV infections. Among the candidates for the development of drugs against CoVs infection, fungal secondary metabolites (SMs) represent an important source to investigate. Herein, antiviral ability of 6-pentyl-α-pyrone (6 PP), a SM obtained by

Indexed as

AhRAntiviral activityCCoVFungal secondary metabolitesIn vitro systemsViral N protein

Identifiers

PMID38545179
PMCPMC10966688
OpenAlexW4393061029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.