Evidence map›Paper›PMID 38544944›Full record

ArticleRSC advances2024

Synthesis, characterization, and biomedical evaluation of ethylene-bridged tetra-NHC Pd(ii), Pt(ii) and Au(iii) complexes, with apoptosis-inducing properties in cisplatin-resistant neuroblastoma cells.

Wolfgang R E Büchele, Tim P Schlachta, Andreas L Gebendorfer, Jenny Pamperin, Leon F Richter, Michael J Sauer, Aram Prokop, Fritz E Kühn

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Wolfgang R E BücheleTechnical University of Munich, School of Natural Sciences, Department of Chemistry and Catalysis Research Center, Molecular Catalysis Lichtenbergstraße 4 85748 Garching Germany fritz.kuehn@ch.tum.de +49 89 289 13477.ORCID https://orcid.org/0009-0006-9092-999X
Tim P SchlachtaTechnical University of Munich, School of Natural Sciences, Department of Chemistry and Catalysis Research Center, Molecular Catalysis Lichtenbergstraße 4 85748 Garching Germany fritz.kuehn@ch.tum.de +49 89 289 13477.ORCID https://orcid.org/0000-0002-6343-2818
Andreas L GebendorferTechnical University of Munich, School of Natural Sciences, Department of Chemistry and Catalysis Research Center, Molecular Catalysis Lichtenbergstraße 4 85748 Garching Germany fritz.kuehn@ch.tum.de +49 89 289 13477.
Jenny PamperinDepartment of Pediatric Oncology/Hematology, Helios Clinics Schwerin Wismarsche Straße 393-397 19055 Schwerin Germany aram.prokop@helios-gesundheit.de.
Leon F RichterTechnical University of Munich, School of Natural Sciences, Department of Chemistry and Catalysis Research Center, Molecular Catalysis Lichtenbergstraße 4 85748 Garching Germany fritz.kuehn@ch.tum.de +49 89 289 13477.ORCID https://orcid.org/0000-0003-2948-9156
Michael J SauerTechnical University of Munich, School of Natural Sciences, Department of Chemistry and Catalysis Research Center, Molecular Catalysis Lichtenbergstraße 4 85748 Garching Germany fritz.kuehn@ch.tum.de +49 89 289 13477.
Aram ProkopDepartment of Pediatric Hematology/Oncology, Children's Hospital Cologne Amsterdamer Straße 59 50735 Cologne Germany.
Fritz E KühnTechnical University of Munich, School of Natural Sciences, Department of Chemistry and Catalysis Research Center, Molecular Catalysis Lichtenbergstraße 4 85748 Garching Germany fritz.kuehn@ch.tum.de +49 89 289 13477.ORCID https://orcid.org/0000-0002-4156-780X
Technical University of Munich · DEMSH Medical School Hamburg – University of Applied Sciences and Medical University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthesis and characterization of the first two cyclic ethylene-bridged tetradentate NHC ligands, with an unsaturated (imidazole) and saturated backbone (2-imidazoline), are described. Complexes of both ligands containing palladium(ii) have been obtained. For platinum(ii) and gold(iii), only the unsaturated tetracarbene complexes could be isolated. The attempts to synthesize a methylene-bridged 2-imidazoline macrocycle are also described. Furthermore, a novel bisimidazolinium ligand precursor and its open-chain Pd

Identifiers

PMID38544944
PMCPMC10967698
OpenAlexW4393240651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.