Evidence map›Paper›PMID 38544857›Full record

ArticleFrontiers in microbiology2024

Mapping the tRNA modification landscape of

Samia Quaiyum, Jingjing Sun, Virginie Marchand, Guangxin Sun, Colbie J Reed, Yuri Motorin, Peter C Dedon, Michael F Minnick, Valérie de Crécy-Lagard

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Compendium of RNA modifications for bacterial stress adaptation.Microbiology and molecular biology reviews : MMBR · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Queuosine salvage inMicrobiology (Reading, England) · 2024
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Samia Quaiyum *Department of Microbiology and Cell Science, University of Florida, Gainesville, FL, United States.
Jingjing Sun *Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States.
Virginie MarchandUniversité de Lorraine, UAR2008/US40 IBSLor, EpiRNA-Seq Core Facility and UMR7365 IMoPA, CNRS-Inserm, Biopôle UL, Nancy, France.
Guangxin SunDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States.
Colbie J ReedDepartment of Microbiology and Cell Science, University of Florida, Gainesville, FL, United States.
Yuri MotorinUniversité de Lorraine, UAR2008/US40 IBSLor, EpiRNA-Seq Core Facility and UMR7365 IMoPA, CNRS-Inserm, Biopôle UL, Nancy, France.
Peter C DedonDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States.
Michael F MinnickDivision of Biological Sciences, University of Montana, Missoula, MT, United States.
Valérie de Crécy-LagardDepartment of Microbiology and Cell Science, University of Florida, Gainesville, FL, United States.
University of Florida · USCentre National de la Recherche Scientifique · FRSingapore-MIT Alliance for Research and Technology · SGMassachusetts Institute of Technology · USUniversity of Montana · US

Funding

Synthesis and function of Queuosine in BacteriaR01GM070641 · NIGMS · UNIVERSITY OF FLORIDA · PI DE CRECY-LAGARD, VALERIE A · 2006 to 2023
$5.3M
Translational regulation in exposure biology: Xenobiotic-induced reprograming oftRNA modifications and selective translation of codon-biased response genes in rat and humanmodelsR01ES026856 · NIEHS · SUNY POLYTECHNIC INSTITUTE · PI Thomas J Begley, Peter C Dedon · 2016 to 2026
$3.9M
Translational Control of ROS ManagementR01ES024615 · NIEHS · SUNY POLYTECHNIC INSTITUTE · PI BEGLEY, THOMAS J · 2014 to 2018
$1.8M
NIEHS NIH HHS R01 ES024615NIEHS NIH HHS R01 ES026856NIGMS NIH HHS R01 GM070641
6 · The paper itself

Abstract

Transfer RNA (tRNA) modifications play a crucial role in maintaining translational fidelity and efficiency, and they may function as regulatory elements in stress response and virulence. Despite their pivotal roles, a comprehensive mapping of tRNA modifications and their associated synthesis genes is still limited, with a predominant focus on free-living bacteria. In this study, we employed a multidisciplinary approach, incorporating comparative genomics, mass spectrometry, and next-generation sequencing, to predict the set of tRNA modification genes responsible for tRNA maturation in two intracellular pathogens-

Indexed as

Bartonellaintracellular pathogensmass spectrometrynext-generation sequencingtRNA modification

Identifiers

PMID38544857
PMCPMC10965804
OpenAlexW4392757757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.