Evidence map›Paper›PMID 38544637›Full record

ArticleCureus2024

A Case Study on the Efficacy of Hypo-Osmotic Swelling Test and Assisted Hatching in Overcoming Necrozoospermia Challenges.

Shivani Khemani, Akash More, Jarul Shrivastava, Namrata Choudhary

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shivani KhemaniClinical Embryology, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Akash MoreClinical Embryology, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Jarul ShrivastavaClinical Embryology, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Namrata ChoudharyClinical Embryology, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report examines the difficulties faced by a couple with 11 years of primary infertility. Based on the diagnostic evaluation, it was determined that the male was a necrozoospermia patient, while the female had unilateral cornual blockage and polycystic ovarian syndrome (PCOS) with diabetes mellitus (DM) symptoms identified. A comprehensive approach was used in the treatment for the female patient, which included a gonadotropin-releasing hormone (GnRH) short antagonist protocol, a GnRH agonist (GnRHa) trigger, assisted hatching (AH), and the use of the hypo-osmotic swelling test (HOST) to gauge the viability of the sperm. The successful outcome, as evidenced by the increasing levels of beta-human chorionic gonadotropin (β-hCG) and a successful embryo transfer, highlights the effectiveness of a customized and multifaceted approach in managing intricate infertility problems. This instance offers insightful information about the way modern reproductive technologies can be successfully integrated with specialized treatment plans to achieve successful outcomes in difficult cases of infertility.

Indexed as

assisted hatchinggnrha triggergnrh short antagonist protocolhypo-osmotic testinfertilitymechanical assisted hatchingnecrozoospermiapcos

Identifiers

PMID38544637
PMCPMC10966423

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.