Evidence map›Paper›PMID 38543859›Full record

ArticleVaccines2024

Sero and Carriage Epidemiology of Pertussis in Urban and Rural Regions in Vietnam.

Michiko Toizumi, Lien Thuy Le, Hien Anh Thi Nguyen, Thao Thi Thu Le, Noriko Kitamura, Liem Xuan Bui, Nen Minh Ho, Hung Thai Do, Kazunari Kamachi, Nao Otsuka and 3 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Michiko ToizumiDepartment of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.ORCID 0000-0002-8401-9344
Lien Thuy LeDepartment of Microbiology and Immunology, The Pasteur Institute in Nha Trang, Nha Trang 650000, Vietnam.ORCID 0000-0002-9526-8573
Hien Anh Thi NguyenNational Institute of Hygiene and Epidemiology, Hanoi 100000, Vietnam.
Thao Thi Thu LeDepartment of Microbiology and Immunology, The Pasteur Institute in Nha Trang, Nha Trang 650000, Vietnam.
Noriko KitamuraCenter for Surveillance, Immunization, and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.ORCID 0000-0002-3418-1028
Liem Xuan BuiQuang Ngai Provincial Center for Disease Control, Quang Ngai 570000, Vietnam.
Nen Minh HoQuang Ngai Provincial Center for Disease Control, Quang Ngai 570000, Vietnam.
Hung Thai DoDepartment of Microbiology and Immunology, The Pasteur Institute in Nha Trang, Nha Trang 650000, Vietnam.
Kazunari KamachiDepartment of Bacteriology II, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.ORCID 0000-0001-5259-1744
Nao OtsukaDepartment of Bacteriology II, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.
Minh Xuan BuiKhanh Hoa Health Service, Nha Trang 650000, Vietnam.
Duc Anh DangNational Institute of Hygiene and Epidemiology, Hanoi 100000, Vietnam.
Lay-Myint YoshidaDepartment of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.ORCID 0000-0002-7567-3248
Institute of Vaccine and Medical Biologicals · VNNational Institute of Infectious Diseases · JPOffice of Extramural Research · USNational Institute Of Hygiene And Epidemiology · VNPham Van Dong University · VN

Funding

Japan Agency for Medical Research and Development JP21wm0125006Japan Society for the Promotion of Science JP17K15829, JP20K18905
6 · The paper itself

Abstract

The underestimation of the pertussis burden prompted our study to investigate the prevalence of recent pertussis infection, its associated factors, and antibody titer changes in the same individuals in Vietnam. Two cross-sectional surveys were conducted in Nha Trang in 2017 and Quang Ngai in 2019, representing high- and low-vaccine-coverage areas, respectively. Serum anti-pertussis toxin immunoglobulin-G (anti-PT IgG) ≥ 62.5 IU/mL by ELISA indicated infection in the previous 12 months. In Nha Trang, the participants of the 2017 survey were followed up in 2019. Logistic regression was used to determine the odds ratios for the characteristics associated with anti-PT IgG ≥ 62.5. The age-stratified prevalence in patients aged >2 years ranged from 2.1% (age 26-35) to 9.6% (3-5) in Nha Trang (2017) and from 7.2% (age 26-35) to 11.4% (6-15) in Quang Ngai. The prevalence tended to be higher in Quang Ngai across all age groups. Cough, recent antibiotic use, and smoking in Nha Trang were positively associated with an anti-PT IgG of ≥62.5, and having been diagnosed with pertussis and persistent cough with paroxysms/whoop in Quang Ngai were positively associated with an anti-PT IgG of ≥62.5. No nasopharyngeal swabs were positive for

Indexed as

anti-pertussis toxin IgGpertussisseroepidemiologyvaccineVietnamwhooping cough

Identifiers

PMID38543859
PMCPMC10974496
OpenAlexW4392105916

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.