Evidence map›Paper›PMID 38543817›Full record

ArticleViruses2024

Comparative Analysis of Cytomegalovirus Gastrointestinal Disease in Immunocompetent and Immunocompromised Patients.

Pai-Jui Yeh, Ren-Chin Wu, Yung-Kuan Tsou, Chien-Ming Chen, Cheng-Tang Chiu, Chien-Chang Chen, Ming-Wei Lai, Yu-Bin Pan, Puo-Hsien Le

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pai-Jui YehDepartment of Pediatric Gastroenterology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0002-3264-5677
Ren-Chin WuInflammatory Bowel Disease Center, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0003-1439-0874
Yung-Kuan TsouDepartment of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Chien-Ming ChenInflammatory Bowel Disease Center, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0001-7829-1504
Cheng-Tang ChiuInflammatory Bowel Disease Center, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Chien-Chang ChenDepartment of Pediatric Gastroenterology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0002-2881-3973
Ming-Wei LaiDepartment of Pediatric Gastroenterology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Yu-Bin PanBiostatistical Section, Clinical Trial Center, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333, Taiwan.ORCID 0000-0002-2004-1526
Puo-Hsien LeInflammatory Bowel Disease Center, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0002-1100-5371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCytomegalovirus (CMV) gastrointestinal (GI) diseases impact both immunocompromised and immunocompetent individuals, yet comprehensive studies highlighting the differences between these groups are lacking.

methodsIn this retrospective study (January 2000 to July 2022) of 401 patients with confirmed CMV GI diseases, we categorized them based on immunological status and compared manifestations, treatments, outcomes, and prognostic factors.

resultsThe immunocompromised patients (n = 193) showed older age, severe illnesses, and higher comorbidity rates. GI bleeding, the predominant manifestation, occurred more in the immunocompetent group (92.6% vs. 63.6%,

conclusionsGI bleeding is the most common manifestation and prognostic factor in both groups. Early diagnosis and effective antiviral therapy can significantly reduce in-hospital mortality.

Indexed as

Cytomegalovirus InfectionsGastrointestinal DiseasesAntiviral AgentsCytomegalovirusGastrointestinal HemorrhageHumansImmunocompromised HostRetrospective StudiesAntiviral Agentsantiviral therapycytomegalovirusgastrointestinal diseaseimmune status

Identifiers

PMID38543817
PMCPMC10974964

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.