Evidence map›Paper›PMID 38543752›Full record

ArticleViruses2024

Genetic Diversity of the Human Adenovirus C Isolated from Hospitalized Children in Russia (2019-2022).

Olga G Kurskaya, Elena A Prokopyeva, Nikita A Dubovitskiy, Mariya V Solomatina, Ivan A Sobolev, Anastasiya A Derko, Alina R Nokhova, Angelika V Anoshina, Natalya V Leonova, Olga A Simkina and 5 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Olga G KurskayaLaboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Elena A ProkopyevaLaboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Nikita A DubovitskiyLaboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.ORCID 0000-0002-7780-1485
Mariya V SolomatinaLaboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.ORCID 0000-0003-0736-0271
Ivan A SobolevLaboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Anastasiya A DerkoLaboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.ORCID 0000-0002-5984-0819
Alina R NokhovaLaboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.ORCID 0000-0002-7891-5847
Angelika V AnoshinaDepartment of Children's Diseases, Novosibirsk Children's Municipal Clinical Hospital №6, Novosibirsk 630015, Russia.
Natalya V LeonovaDepartment of Children's Diseases, Novosibirsk Children's Municipal Clinical Hospital №6, Novosibirsk 630015, Russia.
Olga A SimkinaDepartment of Children's Diseases, Novosibirsk Children's Municipal Clinical Hospital №3, Novosibirsk 630040, Russia.
Tatyana V KomissarovaDepartment of Children's Diseases, Novosibirsk Children's Municipal Clinical Hospital №3, Novosibirsk 630040, Russia.
Alexey E TupikinGenomics Core Facility, Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.
Marsel R KabilovGenomics Core Facility, Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.ORCID 0000-0003-2777-0833
Alexander M ShestopalovLaboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Kirill A SharshovLaboratory of Molecular Epidemiology and Biodiversity of Viruses, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Federal Research Center of Fundamental and Translational Medicine · RUCity Children's Hospital No. 22 · RUInstitute of Chemical Biology and Fundamental Medicine · RU

Funding

Russian Science Foundation 19-74-10055-PState-funded budget project 122012400086-2
6 · The paper itself

Abstract

The human adenovirus (HAdV) is a common pathogen in children that can cause acute respiratory virus infection (ARVI). However, the molecular epidemiological and clinical information relating to HAdV among hospitalized children with ARVI is rarely reported in Russia. A 4-year longitudinal (2019-2022) study among hospitalized children (0-17 years old) with ARVI in Novosibirsk, Russia, was conducted to evaluate the epidemiological and molecular characteristics of HAdV. Statistically significant differences in the detection rates of epidemiological and virological data of all positive viral detections of HAdV were analyzed using a two-tailed Chi-square test. The incidence of HAdV and other respiratory viruses such as human influenza A and B viruses, respiratory syncytial virus, coronavirus, parainfluenza virus, metapneumovirus, rhinovirus, bocavirus, and SARS-CoV-2 was investigated among 3190 hospitalized children using real-time polymerase chain reaction. At least one of these respiratory viruses was detected in 74.4% of hospitalized cases, among which HAdV accounted for 4%. A total of 1.3% co-infections with HAdV were also registered. We obtained full-genome sequences of 12 HAdVs, which were isolated in cell cultures. Genetic analysis revealed the circulation of adenovirus of genotypes C1, C2, C5, C89, and 108 among hospitalized children in the period from 2019-2022.

Indexed as

Adenoviruses, HumanAdenovirus Infections, HumanRespiratory Syncytial Virus, HumanRespiratory Tract InfectionsVirus DiseasesAdolescentChildChild, HospitalizedChild, PreschoolGenetic VariationHospitalizationHumansInfantInfant, NewbornRussiaadenovirus typingC108C2C5C89genotypes C1human adenovirusmolecular epidemiologypediatric infectionsrespiratory virus

Identifiers

PMID38543752
PMCPMC10975726
OpenAlexW4392355756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.