Evidence map›Paper›PMID 38543718›Full record

ArticleViruses2024

Cordycepin Inhibits Enterovirus A71 Replication and Protects Host Cell from Virus-Induced Cytotoxicity through Adenosine Action Pathway.

Yi-Ping Lee, Chun-Keung Yu, Tak-Wah Wong, Li-Ching Chen, Bu-Miin Huang

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yi-Ping LeeDepartment of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Chun-Keung YuDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Tak-Wah WongDepartment of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.ORCID 0000-0002-0131-7339
Li-Ching ChenDepartment of Biological Science & Technology, China Medical University, Taichung 406040, Taiwan.
Bu-Miin HuangDepartment of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
China Medical University · TWNational Cheng Kung University · TWNational Cheng Kung University Hospital · TW

Funding

National Science and Technology Council, Taiwan NSTC 110-2320-B-006-025-MY3
6 · The paper itself

Abstract

Enterovirus A71 (EV-A71) infection typically causes mild illnesses, such as hand-foot-and-mouth disease (HFMD), but occasionally leads to severe or fatal neurological complications in infants and young children. Currently, there is no specific antiviral treatment available for EV-A71 infection. Thus, the development of an effective anti-EV-A71 drug is required urgently. Cordycepin, a major bioactive compound found in

Indexed as

DeoxyadenosinesEnterovirusEnterovirus A, HumanEnterovirus InfectionsHand, Foot and Mouth DiseaseAdenosineAnimalsAntigens, ViralAntiviral AgentsCaco-2 CellsChildChild, PreschoolChlorocebus aethiopsHumansInfantVero CellsAdenosineAntigens, ViralAntiviral AgentscordycepinDeoxyadenosinesadenosine pathwayantiviral activitycordycepinenterovirus A71infectious diseasetraditional herbal medicine

Identifiers

PMID38543718
PMCPMC10974990
OpenAlexW4392156965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.