Evidence map›Paper›PMID 38543705›Full record

ArticleViruses2024

Fast-Track Discovery of SARS-CoV-2-Neutralizing Antibodies from Human B Cells by Direct Functional Screening.

Matthias Hillenbrand, Christoph Esslinger, Jemima Seidenberg, Marcel Weber, Andreas Zingg, Catherine Townsend, Barbara Eicher, Justina Rutkauskaite, Peggy Riese, Carlos A Guzman and 2 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Matthias HillenbrandMemo Therapeutics AG, 8952 Schlieren, Switzerland.ORCID 0000-0001-5047-3429
Christoph EsslingerMemo Therapeutics AG, 8952 Schlieren, Switzerland.
Jemima SeidenbergMemo Therapeutics AG, 8952 Schlieren, Switzerland.
Marcel WeberMemo Therapeutics AG, 8952 Schlieren, Switzerland.
Andreas ZinggMemo Therapeutics AG, 8952 Schlieren, Switzerland.ORCID 0009-0002-7055-4116
Catherine TownsendMemo Therapeutics AG, 8952 Schlieren, Switzerland.
Barbara EicherMemo Therapeutics AG, 8952 Schlieren, Switzerland.
Justina RutkauskaiteMemo Therapeutics AG, 8952 Schlieren, Switzerland.ORCID 0009-0007-3027-2073
Peggy RieseDepartment of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Carlos A GuzmanDepartment of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.ORCID 0000-0002-2913-5254
Karsten FischerMemo Therapeutics AG, 8952 Schlieren, Switzerland.
Simone SchmittMemo Therapeutics AG, 8952 Schlieren, Switzerland.ORCID 0000-0002-8957-1883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the COVID-19 pandemic revealed, rapid development of vaccines and therapeutic antibodies are crucial to guarantee a quick return to the status quo of society. In early 2020, we deployed our droplet microfluidic single-cell-based platform DROPZYLLA

Indexed as

COVID-19PandemicsAntibodies, NeutralizingAntibodies, ViralHEK293 CellsHumansSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, NeutralizingAntibodies, ViralSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antibody discoverymonoclonal antibodiesneutralizing antibodiesSARS-CoV-2viral variants

Identifiers

PMID38543705
PMCPMC10975424

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.