Evidence map›Paper›PMID 38543690›Full record

ArticleViruses2024

Longitudinal and Cross-Sectional Evaluation of Two Commercial Swine Breeding Herds to Characterize Neutralizing Antibody Levels following Porcine Epidemic Diarrhea Virus Outbreaks.

Justin Brown, Kristin Skoland, Heather Kittrell, Josh Ellingson, Paul Thomas, Chelsea Ruston, David Baum, Locke Karriker

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Justin BrownSwine Medicine Education Center, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0002-1892-3300
Kristin SkolandSwine Medicine Education Center, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Heather KittrellSwine Medicine Education Center, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Josh EllingsonAMVC Management Services, Audubon, IA 50025, USA.
Paul ThomasAMVC Management Services, Audubon, IA 50025, USA.
Chelsea RustonSwine Medicine Education Center, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
David BaumDepartment of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Locke KarrikerSwine Medicine Education Center, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0001-6003-1130
Iowa State University · USNational Audubon Society · US

Funding

United States Department of Agriculture 58-5030-5-086
6 · The paper itself

Abstract

Neutralizing antibodies to Porcine Epidemic Diarrhea Virus (PEDV) can be detected by 3 weeks post-infection and remain detectable through at least 24 weeks post-infection. The objective of this study was to evaluate the levels of neutralizing antibodies in sow and piglet serum and sow milk to determine the duration of neutralizing antibodies following PEDV outbreaks. Two farms were selected for the study following outbreaks of PEDV. Monthly, cohorts of sows were sampled and followed through two farrowings. Following each farrowing, samples from piglets and milk were collected. Samples were evaluated for PEDV-neutralizing antibodies by a high-throughput fluorescent neutralization assay. Although neutralizing antibodies to PEDV can be detected throughout 15 months post-outbreak, a decrease in circulating neutralizing antibody levels is noted in farms beginning at six months post-outbreak. With decreasing levels, farms may become more vulnerable to PEDV outbreaks, and practitioners can focus on this time window to implement intervention strategies.

Indexed as

Coronavirus InfectionsPorcine epidemic diarrhea virusSwine DiseasesAnimalsAntibodies, NeutralizingAntibodies, ViralCross-Sectional StudiesFemaleNeutralization TestsSwineAntibodies, NeutralizingAntibodies, Viralneutralizing antibodyporcine epidemic diarrhea virus

Identifiers

PMID38543690
PMCPMC10974537
OpenAlexW4392019055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.