Evidence map›Paper›PMID 38543657›Full record

ArticleMicroorganisms2024

Engineering a Lactobacillus Lysine Riboswitch to Dynamically Control Metabolic Pathways for Lysine Production in

Qingwei Jiang, Feng Geng, Juan Shen, Ping Zhu, Zhaoxin Lu, Libang Zhou, Fengxia Lu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qingwei JiangCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Feng GengCollege of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Juan ShenCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Ping ZhuCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-4393-7608
Zhaoxin LuCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0001-9288-7419
Libang ZhouCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Fengxia LuCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Nanjing Agricultural University · CNBinzhou Medical University · CN

Funding

National Natural Science Foundation of China 31871742
6 · The paper itself

Abstract

Knock-out of genes of metabolic pathways is conventionally used in the metabolic engineering of microorganisms, but it is not applicable for genes of essential pathways. In order to avoid undesirable effects caused by gene deletion, it is attractive to develop riboswitches to dynamically control the metabolic pathways of microbial cell factories. In this regard, the aim of this study is to utilize the lysine riboswitch to control gene expressions of the biosynthetic pathways and by-pathways and thus improve lysine production in

Indexed as

C. glutamicumdynamic controlgene expressionlysine riboswitchmetabolic pathway

Identifiers

PMID38543657
PMCPMC10974012
OpenAlexW4392908850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.