Evidence map›Paper›PMID 38543516›Full record

ArticleMicroorganisms2024

Repositioning of the Antihyperlipidemic Drug Fenofibrate for the Management of

Roberto M Guerra, Maria José Figueras, Isabel Pujol-Bajador, Ana Fernández-Bravo

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Fenofibrate suppressesFrontiers in cellular and infection microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Roberto M GuerraUnit of Microbiology, Department of Basic Health Sciences, Faculty of Medicine and Health Sciences, Institut d'Investigació Sanitària Pere Virgili (IISPV), University Rovira i Virgili, 43201 Reus, Spain.ORCID 0000-0002-0126-1750
Maria José FiguerasUnit of Microbiology, Department of Basic Health Sciences, Faculty of Medicine and Health Sciences, Institut d'Investigació Sanitària Pere Virgili (IISPV), University Rovira i Virgili, 43201 Reus, Spain.
Isabel Pujol-BajadorUnit of Microbiology, Department of Basic Health Sciences, Faculty of Medicine and Health Sciences, Institut d'Investigació Sanitària Pere Virgili (IISPV), University Rovira i Virgili, 43201 Reus, Spain.
Ana Fernández-BravoUnit of Microbiology, Department of Basic Health Sciences, Faculty of Medicine and Health Sciences, Institut d'Investigació Sanitària Pere Virgili (IISPV), University Rovira i Virgili, 43201 Reus, Spain.ORCID 0000-0001-7637-5958
Institut de Recerca Biomèdica Catalunya Sud · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fenofibrate is a fibric acid derivative used as an antihyperlipidemic drug in humans. Its active metabolite, fenofibric acid, acts as an agonist to the peroxisome proliferator-activated receptor alpha (PPAR-α), a transcription factor involved in different metabolic pathways. Some studies have reported the potential protective role of this drug in cell lines and in vivo models against bacterial and viral infections. The aim of this study was to assess the in vitro effect of fenofibrate in the macrophage cell line J744A.1 against infections produced by

Indexed as

Aeromonasantimicrobial resistancedrug repositioningfenofibrateimmune responseinfection

Identifiers

PMID38543516
PMCPMC10972371
OpenAlexW4392166518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.