Evidence map›Paper›PMID 38543475›Full record

ReviewMicroorganisms2024

The Gut Microbiome in the First One Thousand Days of Neurodevelopment: A Systematic Review from the Microbiome Perspective.

Nathalia F Naspolini, Paulo A Schüroff, Maria J Figueiredo, Gabriela E Sbardellotto, Frederico R Ferreira, Daniel Fatori, Guilherme V Polanczyk, Alline C Campos, Carla R Taddei

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nathalia F NaspoliniSchool of Arts, Sciences and Humanity, University of São Paulo, São Paulo 03828-000, Brazil.
Paulo A SchüroffSchool of Arts, Sciences and Humanity, University of São Paulo, São Paulo 03828-000, Brazil.ORCID 0000-0002-7808-7818
Maria J FigueiredoDepartment of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, São Paulo 14049-900, Brazil.ORCID 0000-0003-2188-2383
Gabriela E SbardellottoDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0001-6281-2387
Frederico R FerreiraOswaldo Cruz Foundation, Oswaldo Cruz Institute, Av. Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0001-5098-9775
Daniel FatoriDepartment of Psychiatry, Medical School FMUSP, University of São Paulo, São Paulo 05403-903, Brazil.
Guilherme V PolanczykDepartment of Psychiatry, Medical School FMUSP, University of São Paulo, São Paulo 05403-903, Brazil.ORCID 0000-0003-2311-3289
Alline C CamposDepartment of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, São Paulo 14049-900, Brazil.
Carla R TaddeiSchool of Arts, Sciences and Humanity, University of São Paulo, São Paulo 03828-000, Brazil.ORCID 0000-0003-0869-0651
Universidade de São Paulo · BRFundação Oswaldo Cruz · BR

Funding

Wellcome Trust
6 · The paper itself

Abstract

Evidence shows that the gut microbiome in early life is an essential modulator of physiological processes related to healthy brain development, as well as mental and neurodegenerative disorders. Here, we conduct a systematic review of gut microbiome assessments on infants (both healthy and with conditions that affect brain development) during the first thousand days of life, associated with neurodevelopmental outcomes, with the aim of investigating key microbiome players and mechanisms through which the gut microbiome affects the brain.

Indexed as

BacteroidesBifidobacteriumearly life microbiomemicrobial mechanismmicrobiome–gut–brain axisneurodevelopmental outcomes

Identifiers

PMID38543475
PMCPMC10972197
OpenAlexW4391985721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.