Evidence map›Paper›PMID 38543286›Full record

ArticlePharmaceutics2024

Amide-to-Triazole Switch in Somatostatin-14-Based Radioligands: Impact on Receptor Affinity and In Vivo Stability.

Xabier Guarrochena, Panagiotis Kanellopoulos, Anna Stingeder, Lisa-Maria Rečnik, Irene V J Feiner, Marie Brandt, Wolfgang Kandioller, Theodosia Maina, Berthold A Nock, Thomas L Mindt

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Xabier GuarrochenaInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria.ORCID 0009-0004-0049-4829
Panagiotis KanellopoulosMolecular Radiopharmacy, INRaSTES, NCSR "Demokritos", 15341 Athens, Greece.ORCID 0000-0002-0617-3936
Anna StingederLudwig Boltzmann Institute Applied Diagnostics, AKH Wien c/o Sekretariat Nuklearmedizin, Währinger Gürtel 18-20, 1090 Vienna, Austria.
Lisa-Maria RečnikInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria.
Irene V J FeinerInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria.ORCID 0000-0001-6938-9745
Marie BrandtInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria.ORCID 0000-0001-8685-7352
Wolfgang KandiollerInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Str. 42, 1090 Vienna, Austria.ORCID 0000-0002-5630-712X
Theodosia MainaMolecular Radiopharmacy, INRaSTES, NCSR "Demokritos", 15341 Athens, Greece.ORCID 0000-0002-1123-2486
Berthold A NockMolecular Radiopharmacy, INRaSTES, NCSR "Demokritos", 15341 Athens, Greece.ORCID 0000-0002-6028-9112
Thomas L MindtInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria.ORCID 0000-0002-2090-1725
University of Vienna · ATNational Centre of Scientific Research "Demokritos" · GRLudwig Boltzmann Institute Applied Diagnostics · AT

Funding

Austrian Science Fund FWF P 31477FWF Austrian Science Fund P 31477-B28University of Vienna Open Access Funding
6 · The paper itself

Abstract

The use of metabolically stabilized, radiolabeled somatostatin (SST) analogs ([

Indexed as

1,4-disubstituted 1,2,3-triazoleamide-to-triazole substitutionbioisosteresEntresto®metabolic stabilityneprilysinpansomatostatinpeptide-based radiotracersomatostatintriazolo-peptidomimetic

Identifiers

PMID38543286
PMCPMC10976246
OpenAlexW4392747332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.