Evidence map›Paper›PMID 38543205›Full record

ArticlePharmaceutics2024

Breast Cancer Treatment Using the Magneto-Hyperthermia Technique Associated with Omega-3 Polyunsaturated Fatty Acids' Supplementation and Physical Training.

Matheus Haubert Theinel, Mariana Penteado Nucci, Gabriela Cianciarullo, Fernando Anselmo Oliveira, Arielly da Hora Alves, Javier Bustamante Mamani, Gabriel Nery de Albuquerque Rego, Nicole Mastandrea Ennes do Valle, Olívia Furiama Metropolo Dias, Cícero Júlio Silva Costa and 4 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Matheus Haubert TheinelHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0002-9342-1327
Mariana Penteado NucciLIM44-Hospital das Clínicas da Faculdade Medicina da Universidade de São Paulo, São Paulo 05403-000, SP, Brazil.ORCID 0000-0002-1502-9215
Gabriela CianciarulloHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0002-8561-9034
Fernando Anselmo OliveiraHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0002-7226-1694
Arielly da Hora AlvesHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0003-3570-0827
Javier Bustamante MamaniHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0001-5038-0070
Gabriel Nery de Albuquerque RegoHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.
Nicole Mastandrea Ennes do ValleHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0003-4523-1753
Olívia Furiama Metropolo DiasHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0003-0168-9367
Cícero Júlio Silva CostaHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0003-1707-5917
Felipe Lima NascimentoHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.
Juan Matheus MunozHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0002-4473-1644
Andressa Arruda de MoraesHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.
Lionel Fernel GamarraHospital Israelita Albert Einstein, São Paulo 05652-000, SP, Brazil.ORCID 0000-0002-3910-0047
Hospital Israelita Albert Einstein · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) presents a growing global concern, mainly for the female population of working age. Their pathophysiology shows challenges when attempting to ensure conventional treatment efficacy without adverse effects. This study aimed to evaluate the efficacy of magneto-hyperthermia (MHT) therapy associated with supplementation with omega-3 polyunsaturated fatty acid (w-3 PUFA) and engagement in physical training (PT) for the triple-negative BC (TNBC) model. First, we assessed the physicochemical properties of iron oxide nanoparticles (ION) in biological conditions, as well as their heating potential for MHT therapy. Then, a bioluminescence (BLI) evaluation of the best tumor growth conditions in the TNBC model (the quantity of implanted cells and time), as well as the efficacy of MHT therapy (5 consecutive days) associated with the previous administration of 8 weeks of w-3 PUFA and PT, was carried out. The results showed the good stability and potential of ION for MHT using 300 Gauss and 420 kHz. In the TNBC model, adequate tumor growth was observed after 14 days of 2 × 10

Indexed as

bioluminescence imagingbreast cancercancer treatmentiron oxide nanoparticlesmagnetic-hyperthermiaomega-3physical exercisepolyunsaturated fatty

Identifiers

PMID38543205
PMCPMC10976084
OpenAlexW4392034008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.