Evidence map›Paper›PMID 38543163›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Synthesis, Computational Study, and In Vitro α-Glucosidase Inhibitory Action of 1,3,4-Thiadiazole Derivatives of 3-Aminopyridin-2(1

Zarina Shulgau, Irina V Palamarchuk, Shynggys Sergazy, Assel Urazbayeva, Yerlan Ramankulov, Ivan V Kulakov

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zarina ShulgauNational Laboratory Astana, Nazarbayev University, Kabanbai Batyr Ave. 53, Astana Z05H0P9, Kazakhstan.ORCID 0000-0001-8148-0816
Irina V PalamarchukHigher School of Natural Science, University of Tyumen, 15a Perekopskaya St., Tyumen 625003, Russia.ORCID 0000-0003-3376-6953
Shynggys SergazyNational Laboratory Astana, Nazarbayev University, Kabanbai Batyr Ave. 53, Astana Z05H0P9, Kazakhstan.ORCID 0000-0002-6030-620X
Assel UrazbayevaNational Laboratory Astana, Nazarbayev University, Kabanbai Batyr Ave. 53, Astana Z05H0P9, Kazakhstan.ORCID 0009-0003-9555-059X
Yerlan RamankulovSchool of Science and Technology, Nazarbayev University, Kabanbai Batyr Ave. 53, Astana Z05H0P9, Kazakhstan.ORCID 0000-0001-6786-3028
Ivan V KulakovNational Center for Biotechnology, 13/5 Kurgalzhynskoe Road, Astana Z05K8D5, Kazakhstan.ORCID 0000-0001-5772-2096
National Center for Biotechnology · KZUniversity of Tyumen · RUNazarbayev University · KZ

Funding

Ministry of Education and Science of the Republic of Kazakhstan AP14871433
6 · The paper itself

Abstract

This article reports on the synthesis of nine promising new 1,3,4-thiadiazole derivatives based on 3-aminopyridones, containing various acidic linkers. The synthesis was carried out by cyclizing the corresponding thiohydrazides

Indexed as

1,3,4-thiadiazole derivatives3-aminopyridin-2(1H)-onesantidiabetic activityIC50molecular dockingmonothiooxamidesoxamic acid thiohydrazidesα-glucosidase inhibition

Identifiers

PMID38543163
PMCPMC10974052
OpenAlexW4392861404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.