Evidence map›Paper›PMID 38543086›Full record

ReviewPharmaceuticals (Basel, Switzerland)2024

Magnetic Hyperthermia Therapy for High-Grade Glioma: A State-of-the-Art Review.

Benjamin Rodriguez, Daniel Rivera, Jack Y Zhang, Cole Brown, Tirone Young, Tyree Williams, Sakibul Huq, Milena Mattioli, Alexandros Bouras, Constantinos G Hadjpanayis

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Magnetic nanoparticles as promising materials for the future of medicine.Journal of materials science. Materials in medicine · 2026
    Review
  8. Review
  9. Chitosan-Coated FeMaterials (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Benjamin RodriguezIcahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-4735-4773
Daniel RiveraIcahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jack Y ZhangIcahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Cole BrownIcahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-4805-0042
Tirone YoungIcahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Tyree WilliamsSinai BioDesign, Department of Neurosurgery, Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-1651-9048
Sakibul HuqDepartment of Neurological Surgery, UPMC, Pittsburgh, PA 15213, USA.
Milena MattioliBrain Tumor Nanotechnology Laboratory, UPMC Hillman Cancer Center, Pittsburgh, PA 15213, USA.
Alexandros BourasBrain Tumor Nanotechnology Laboratory, UPMC Hillman Cancer Center, Pittsburgh, PA 15213, USA.
Constantinos G HadjpanayisDepartment of Neurological Surgery, UPMC, Pittsburgh, PA 15213, USA.
Icahn School of Medicine at Mount Sinai · USMount Sinai Hospital · USUPMC Hillman Cancer Center · USNeurological Surgery · USUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic hyperthermia therapy (MHT) is a re-emerging treatment modality for brain tumors where magnetic nanoparticles (MNPs) are locally delivered to the brain and then activated with an external alternating magnetic field (AMF) to generate localized heat at a site of interest. Due to the recent advancements in technology and theory surrounding the intervention, clinical and pre-clinical trials have demonstrated that MHT may enhance the effectiveness of chemotherapy and radiation therapy (RT) for the treatment of brain tumors. The future clinical success of MHT relies heavily on designing MNPs optimized for both heating and imaging, developing reliable methods for the local delivery of MNPs, and designing AMF systems with integrated magnetic particle imaging (MPI) for use in humans. However, despite the progression of technological development, the clinical progress of MHT has been underwhelming. This review aims to summarize the current state-of-the-art of MHT and offers insight into the current barriers and potential solutions for moving MHT forward.

Indexed as

gliomaHGG = High Grade GliomahyperthermiaMHT: Magnetic Hyperthermia TherapyMNP = Magnetic Nanoparticle

Identifiers

PMID38543086
PMCPMC10976112
OpenAlexW4392156795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.