Evidence map›Paper›PMID 38543065›Full record

ReviewPharmaceuticals (Basel, Switzerland)2024

Pharmacokinetics and Pharmacodynamics: A Comprehensive Analysis of the Absorption, Distribution, Metabolism, and Excretion of Psychiatric Drugs.

Zainab Zakaraya, Mohammad Abu Assab, Lina N Tamimi, Nida Karameh, Mohammad Hailat, Laila Al-Omari, Wael Abu Dayyih, Omar Alasasfeh, Mohammad Awad, Riad Awad

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. New Personalized Medicine Model for Medication Management.Journal of personalized medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zainab ZakarayaFaculty of Pharmacy, Al-Ahliyya Amman University, Amman 19111, Jordan.ORCID 0000-0003-3691-9759
Mohammad Abu AssabFaculty of Pharmacy, Zarqa University, Zarqa 13132, Jordan.
Lina N TamimiFaculty of Pharmacy, Zarqa University, Zarqa 13132, Jordan.
Nida KaramehFaculty of Pharmacy, Al-Ahliyya Amman University, Amman 19111, Jordan.
Mohammad HailatFaculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman 11733, Jordan.ORCID 0000-0003-4263-0134
Laila Al-OmariFaculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman 19111, Jordan.
Wael Abu DayyihFaculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.ORCID 0000-0002-5832-7247
Omar AlasasfehFaculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.
Mohammad AwadFaculty of Pharmacy and Medical Sciences, University of Petra, Amman 11196, Jordan.
Riad AwadFaculty of Pharmacy and Medical Sciences, University of Petra, Amman 11196, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The two main classifications of antidepressant medications are selective norepinephrine reuptake inhibitors (SNRIs) and selective serotonin reuptake inhibitors (SSRIs). Out of the available choices, selective serotonin reuptake inhibitors (SSRIs) have emerged as the most commonly prescribed option. The class demonstrates a greater degree of diversity in its structural characteristics in contrast to its neurochemical effects. Nevertheless, it is important to acknowledge that the chemical composition of a drug within this specific class does not carry substantial significance in the selection process. A comprehensive analysis of the pharmacodynamic and pharmacodynamic properties of antidepressant drugs proves advantageous for clinicians and managed care providers responsible for selecting preferred selective serotonin reuptake inhibitors (SSRIs) from a roster of authorized medications. The physicochemical characteristics, which possess considerable significance, are frequently disregarded except during the drug development stage. Pharmacodynamic properties refer to the physiological and biochemical effects that drugs exert on the human body. It is noteworthy that the inclusion of selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) in a comprehensive depression management protocol may demonstrate enhanced effectiveness in clinical environments as opposed to controlled trials.

Indexed as

absorptiondistributionexcretionmetabolismpharmacodynamicspharmacokineticspsychiatric drugs

Identifiers

PMID38543065
PMCPMC10974343

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.