Selective Generation of Aldimine and Ketimine Tautomers of the Schiff Base Condensates of Amino Acids with Imidazole Aldehydes or of Imidazole Methanamines with Pyruvates-Isomeric Control with 2- vs. 4-Substituted Imidazoles.

Greg Brewer, Cynthia Brewer, Raymond J Butcher, Peter Zavalij

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.7field-weighted citation impact, top 35% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

Chirality Transfer and Thiazolidine or Thiazine Formation in Reactions of L and D Enantiomers of β- or γ-Sulfhydryl Amino Acids with Imidazole Carboxaldehydes and Nickel(II).Molecules (Basel, Switzerland) · 2026
Article
Chirality Transfer and Oxazolidine Formation in Reaction of L and D Enantiomers of β-Hydroxy Amino Acids with Nitrogenous Carboxaldehydes and Nickel(II).Molecules (Basel, Switzerland) · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Greg BrewerDepartment of Chemistry, The Catholic University of America, Washington, DC 20064, USA.

Cynthia BrewerDepartment of Chemistry, The Catholic University of America, Washington, DC 20064, USA.

Raymond J ButcherDepartment of Chemistry, Howard University, Washington, DC 20059, USA.ORCID 0000-0003-2770-7076

Peter ZavalijDepartment of Chemistry, University of Maryland, College Park, MD 20742, USA.

University of America · USHoward University · USUniversity of Maryland, College Park · US

Funding

NASA NNX15AM13A

6 · The paper itself

Abstract

The Schiff base condensation of 5-methyl-4-imidazole carboxaldehyde, 5Me4ImCHO, and the anion of an amino acid, H

Indexed as

aldimineamino acidshomochiralityimidazoleketiminepyruvatesSchiff basetautomerization

Identifiers

PMID38542960

DOI10.3390/molecules29061324

PMCPMC10974184

OpenAlexW4392918313

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.