Evidence map›Paper›PMID 38542913›Full record

ArticleMolecules (Basel, Switzerland)2024

Antimicrobial Activity of 2-(Piperazin-1-yl)naphtho[2,3-d]thiazole-4,9-dione against Staphylococcus Strains.

Tamami Haraguchi, Saki Hayashi, Seira Nakasaka, Yoshiro Hatanaka, Toshihiro Nagao, Shigemitsu Tanaka, Miki Yoshii, Fumiko Hara, Masayori Hagimori, Miyako Yoshida

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tamami HaraguchiDepartment of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Mukogawa Women's University, 11-68 Koshien 9-Bancho, Nishinomiya 663-8179, Hyogo, Japan.
Saki HayashiDepartment of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Mukogawa Women's University, 11-68 Koshien 9-Bancho, Nishinomiya 663-8179, Hyogo, Japan.
Seira NakasakaDepartment of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Mukogawa Women's University, 11-68 Koshien 9-Bancho, Nishinomiya 663-8179, Hyogo, Japan.
Yoshiro HatanakaOsaka Research Institute of Industrial Science and Technology, 1-6-50 Morinomiya, Joto-ku, Osaka 536-8553, Osaka, Japan.
Toshihiro NagaoOsaka Research Institute of Industrial Science and Technology, 1-6-50 Morinomiya, Joto-ku, Osaka 536-8553, Osaka, Japan.
Shigemitsu TanakaOsaka Research Institute of Industrial Science and Technology, 1-6-50 Morinomiya, Joto-ku, Osaka 536-8553, Osaka, Japan.
Miki YoshiiOsaka Research Institute of Industrial Science and Technology, 1-6-50 Morinomiya, Joto-ku, Osaka 536-8553, Osaka, Japan.
Fumiko HaraDepartment of Analitical Chemistry, Faculty of Pharmaceutical Sciences, Mukogawa Women's University, 11-68 Koshien 9-Bancho, Nishinomiya 663-8179, Hyogo, Japan.ORCID 0000-0003-3025-6720
Masayori HagimoriDepartment of Analitical Chemistry, Faculty of Pharmaceutical Sciences, Mukogawa Women's University, 11-68 Koshien 9-Bancho, Nishinomiya 663-8179, Hyogo, Japan.ORCID 0000-0002-2371-911X
Miyako YoshidaDepartment of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Mukogawa Women's University, 11-68 Koshien 9-Bancho, Nishinomiya 663-8179, Hyogo, Japan.
Mukogawa Women's University · JPOsaka Research Institute of Industrial Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an urgent need to discover and develop novel antibacterial agents. Accordingly, we synthesised 2-(piperazin-1-yl)naphtho[2,3-d]thiazole-4,9-dione (PNT), which exhibits antimicrobial activity. The aim of this study was to characterise PNT as an effective antimicrobial agent. Fluorescence microscopy was used to measure PNT's uptake into microbial cells (strains of

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcusAnti-Bacterial AgentsDNA GyraseMicrobial Sensitivity TestsThiazolesAnti-Bacterial AgentsDNA GyraseThiazoles2-(piperazin-1-yl)naphtho[2,3-d]thiazole-4,9-dioneantimicrobialDNA gyrasefluorescencetransmission electron microscopy

Identifiers

PMID38542913
PMCPMC10975047
OpenAlexW4392762094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.