Evidence map›Paper›PMID 38542876›Full record

ArticleMolecules (Basel, Switzerland)2024

Saponins from

Li Liu, Liang Qiu, Jing Xue, Chao Zhong, Manman Qin, Yifeng Zhang, Chuanming Xu, Yanfei Xie, Jun Yu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Ginsenoside RbChinese herbal medicines · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Li LiuCenter for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.ORCID 0009-0003-3912-5046
Liang QiuCenter for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Jing XueCenter for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Chao ZhongCenter for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.ORCID 0009-0007-4780-0696
Manman QinCenter for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Yifeng ZhangCenter for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Chuanming XuCenter for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.ORCID 0000-0001-7082-2833
Yanfei XieCenter for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Jun YuDepartment of Cardiovascular Sciences and Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0003-4530-2179
Jiangxi University of Traditional Chinese Medicine · CNTemple University · US

Funding

the Jiangxi Provincial Natural Science Foundation 20212BAB206008the National Natural Science Foundation of China 82160051
6 · The paper itself

Abstract

Endothelial inflammation is a multifaceted physiological process that plays a pivotal role in the pathogenesis and progression of diverse diseases, encompassing but not limited to acute lung infections like COVID-19, coronary artery disease, stroke, sepsis, metabolic syndrome, certain malignancies, and even psychiatric disorders such as depression. This inflammatory response is characterized by augmented expression of adhesion molecules and secretion of pro-inflammatory cytokines. In this study, we discovered that saponins from

Indexed as

Acute Lung InjuryChiveDrugs, Chinese HerbalSaponinsAnimalsHumansHuman Umbilical Vein Endothelial CellsInflammationInflammation MediatorsLipopolysaccharidesMiceNF-kappa BTumor Necrosis Factor-alphaVascular Cell Adhesion Molecule-1allii macrostemonis bulbusDrugs, Chinese HerbalInflammation MediatorsLipopolysaccharidesNF-kappa BSaponinsTumor Necrosis Factor-alphaVascular Cell Adhesion Molecule-1acute lung injuryendothelial inflammationsaponins from Allium macrostemon bulbsVCAM-1

Identifiers

PMID38542876
PMCPMC10976117
OpenAlexW4392661116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.