Evidence map›Paper›PMID 38542770›Full record

ArticleNutrients2024

Exploring the Gut Microbiome and Metabolome in Individuals with Alopecia Areata Disease.

Olga Nikoloudaki, Daniela Pinto, Marta Acin Albiac, Giuseppe Celano, Alessio Da Ros, Maria De Angelis, Fabio Rinaldi, Marco Gobbetti, Raffaella Di Cagno

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Cutaneous and Gut Dysbiosis in Alopecia Areata: A Review.JID innovations : skin science from molecules to population health · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Olga NikoloudakiFaculty of Agricultural, Environmental and Food Sciences, Free University of Bozen-Bolzano, 39100 Bolzano, Italy.ORCID 0000-0002-2985-9033
Daniela PintoHuman Microbiome Advanced Project (HMAP), Giuliani S.p.A, 20129 Milan, Italy.ORCID 0000-0001-8107-106X
Marta Acin AlbiacFaculty of Agricultural, Environmental and Food Sciences, Free University of Bozen-Bolzano, 39100 Bolzano, Italy.
Giuseppe CelanoDepartment of Soil, Plant and Food Science, University of Bari Aldo Moro, 70121 Bari, Italy.ORCID 0000-0002-3805-7681
Alessio Da RosFaculty of Agricultural, Environmental and Food Sciences, Free University of Bozen-Bolzano, 39100 Bolzano, Italy.ORCID 0000-0002-6603-7522
Maria De AngelisDepartment of Soil, Plant and Food Science, University of Bari Aldo Moro, 70121 Bari, Italy.ORCID 0000-0002-2010-884X
Fabio RinaldiHuman Microbiome Advanced Project (HMAP), Giuliani S.p.A, 20129 Milan, Italy.
Marco GobbettiFaculty of Agricultural, Environmental and Food Sciences, Free University of Bozen-Bolzano, 39100 Bolzano, Italy.
Raffaella Di CagnoFaculty of Agricultural, Environmental and Food Sciences, Free University of Bozen-Bolzano, 39100 Bolzano, Italy.
Free University of Bozen-Bolzano · ITGiuliani (Italy) · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, heightened attention has been devoted to unravelling the intricate interplay between genetic and environmental factors shaping the gut microbiota and its significance for human health. This study delves into exploring the plausible connection between Alopecia Areata (AA), an autoimmune disease, and the dynamics of the gut microbiome. Examining a cohort of healthy adults and individuals with AA, both the gut microbiota composition and volatile organic compound (VOC) metabolites from faeces and urine were analysed. While overall microbiota composition showed no significant differences, intra-individual variability revealed distinctions related to age, gender, and pathology status, with AA individuals exhibiting reduced species richness and evenness. Differential abundance analysis identified microbial biomarkers for AA, notably Firmicutes,

Indexed as

Alopecia AreataGastrointestinal MicrobiomeAdultBiomarkersFecesHumansMetabolomeRNA, Ribosomal, 16SBiomarkersRNA, Ribosomal, 16Salopecia areatabiomarkersgut microbiomeimmunoregulationmetabolome

Identifiers

PMID38542770
PMCPMC10975414
OpenAlexW4392856768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.