Evidence map›Paper›PMID 38542762›Full record

ArticleNutrients2024

Glutathione Supplementation Prevents Neonatal Parenteral Nutrition-Induced Short- and Long-Term Epigenetic and Transcriptional Disruptions of Hepatic H

Angela Mungala Lengo, Ibrahim Mohamed, Jean-Claude Lavoie

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Angela Mungala LengoCHU Sainte-Justine, Department of Nutrition, Université de Montréal, Montreal, QC H3T 1C5, Canada.
Ibrahim MohamedCHU Sainte-Justine, Department of Pediatrics-Neonatology, Université de Montréal, Montreal, QC H3T 1C5, Canada.ORCID 0000-0002-9860-0279
Jean-Claude LavoieCHU Sainte-Justine, Department of Nutrition, Université de Montréal, Montreal, QC H3T 1C5, Canada.ORCID 0000-0002-5910-0300
Centre Hospitalier Universitaire Sainte-Justine · CA

Funding

CIHR PJT-148522
6 · The paper itself

Abstract

The parenteral nutrition (PN) received by premature newborns is contaminated with peroxides that induce global DNA hypermethylation via oxidative stress. Exposure to peroxides could be an important factor in the induction of chronic diseases such as those observed in adults who were born preterm. As endogenous H

Indexed as

Hydrogen PeroxideNF-E2-Related Factor 2AnimalsAnimals, NewbornDietary SupplementsEpigenesis, GeneticGlutathioneGlutathione DisulfideGuinea PigsKelch-Like ECH-Associated Protein 1Parenteral NutritionPeroxidesRNA, MessengerGlutathioneGlutathione DisulfideHydrogen PeroxideKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2PeroxidesRNA, Messengerdevelopmental programmingGCLCGPx1GSaseintravenous GSSGneonatal nutritionNrf2nutrigenomicsoxidative stressSOD2

Identifiers

PMID38542762
PMCPMC10975225
OpenAlexW4392856763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.