Evidence map›Paper›PMID 38542531›Full record

ArticleInternational journal of molecular sciences2024

In Vitro Antibacterial Activity of Ozonated Olive Oil against Bacteria of Various Antimicrobial Resistance Profiles Isolated from Wounds of Companion Animals.

Anna Lenart-Boroń, Klaudia Stankiewicz, Klaudia Bulanda, Natalia Czernecka, Miłosz Heliasz, Walter Hunter, Anna Ratajewicz, Karen Khachatryan, Gohar Khachatryan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Anna Lenart-BorońDepartment of Microbiology and Biomonitoring, Faculty of Agriculture and Economics, University of Agriculture in Kraków, Adam Mickiewicz Ave. 24/28, 30-059 Kraków, Poland.ORCID 0000-0003-3655-7567
Klaudia StankiewiczDepartment of Microbiology and Biomonitoring, Faculty of Agriculture and Economics, University of Agriculture in Kraków, Adam Mickiewicz Ave. 24/28, 30-059 Kraków, Poland.
Klaudia BulandaDepartment of Forest Ecosystems Protection, Faculty of Forestry, University of Agriculture in Kraków, 29 Listopada Ave. 46, 31-425 Kraków, Poland.
Natalia CzerneckaScientific Circle of Biotechnologists, Faculty of Biotechnology and Horticulture, University of Agriculture in Kraków, 29 Listopada Ave. 54, 31-425 Kraków, Poland.
Miłosz HeliaszScientific Circle of Biotechnologists, Faculty of Biotechnology and Horticulture, University of Agriculture in Kraków, 29 Listopada Ave. 54, 31-425 Kraków, Poland.ORCID 0009-0000-9618-602X
Walter HunterScientific Circle of Biotechnologists, Faculty of Biotechnology and Horticulture, University of Agriculture in Kraków, 29 Listopada Ave. 54, 31-425 Kraków, Poland.
Anna RatajewiczScientific Circle of Biotechnologists, Faculty of Biotechnology and Horticulture, University of Agriculture in Kraków, 29 Listopada Ave. 54, 31-425 Kraków, Poland.
Karen KhachatryanLaboratory of Nanomaterials and Nanotechnology, Faculty of Food Technology, University of Agriculture, Balicka Street 122, 30-149 Kraków, Poland.ORCID 0000-0001-7823-5406
Gohar KhachatryanDepartment of Food Quality Analysis and Assessment, Faculty of Food Technology, University of Agriculture, Balicka Street 122, 30-149 Kraków, Poland.ORCID 0000-0002-4601-7145
University of Agriculture in Krakow · PL

Funding

Ministry of Science and Higher Education SKN/SP/569551/2023
6 · The paper itself

Abstract

Frequent colonization and bacterial infection of skin wounds in small animals prevent or impair their healing. However, the broadly applied antimicrobial therapy of wounds is not always necessary and promotes the spread of bacterial resistance. Thus, alternatives to antimicrobial therapy, including preventive measures in the form of wound dressings with antibiotic properties, should be searched for. The aim of this study was to develop a new, efficient, cost-effective and non-toxic formulation with antimicrobial properties to serve as an alternative to antibiotic administration in wound-healing stimulation in companion animals. Nano/microencapsulated ozonated olive oil in a hyaluronan matrix was developed, with ozone concentration high enough to prevent bacterial growth. The presence and size of nano- and microcapsules were determined with scanning electron microscopy (SEM). Antibacterial activity of developed formulations was examined in vitro on 101 Gram-positive and Gram-negative bacteria isolated from the wounds of companion animals. The highest ozone concentration in the developed formulations inhibited the growth of 40.59% bacteria. Species and genus-specific differences in reactions were observed.

Indexed as

Bacterial InfectionsOzoneAnimalsAnti-Bacterial AgentsBacteriaDrug Resistance, BacterialGram-Negative BacteriaGram-Positive BacteriaOlive OilPetsAnti-Bacterial AgentsOlive OilOzoneantibacterial activityozonescanning electron microscopytopical dressingsveterinary medicinewound infections

Identifiers

PMID38542531
PMCPMC10971217
OpenAlexW4393036887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.