Evidence map›Paper›PMID 38542481›Full record

ArticleInternational journal of molecular sciences2024

Christopher J Occhiuto, Karen T Liby

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher J OcchiutoDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-2218-4504
Karen T LibyDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.ORCID 0000-0003-3317-3437
Indiana University School of Medicine

Funding

Multi-Radical Protein Footprinting (MRPF™) PlatformR44GM142351 · NIGMS · GENNEXT TECHNOLOGIES, INC. · PI WEINBERGER, SCOT RANDY · 2024 to 2025
$2.5M
Integrative Pharmacological Sciences Training Program (IPSTP)T32GM142521 · NIGMS · MICHIGAN STATE UNIVERSITY · PI ANNE M. DORRANCE, Gina Marie Leinninger · 2021 to 2026
$2.4M
Nrf2, immune cells and lung cancerR01CA226690 · NCI · MICHIGAN STATE UNIVERSITY · PI LIBY, KAREN T. · 2019 to 2023
$1.6M
Multi-Wavelength Fluorescence Radical Dosimetry for Real-Time Assessment of Protein Footprinting Radical YieldR43GM142351 · NIGMS · GENNEXT TECHNOLOGIES, INC. · PI WEINBERGER, SCOT RANDY · 2021 to 2021
$251k
NCI NIH HHS R01 CA226690NIGMS NIH HHS GM142351NIGMS NIH HHS R43 GM142351NIGMS NIH HHS R44 GM142351NIGMS NIH HHS T32 GM142521
6 · The paper itself

Abstract

Considerable advances have been made in lung cancer therapies, but there is still an unmet clinical need to improve survival for lung cancer patients. Immunotherapies have improved survival, although only 20-30% of patients respond to these treatments. Interestingly, cancers with mutations in Kelch-like ECH-associated protein 1 (

Indexed as

Lung NeoplasmsAnimalsHumansKelch-Like ECH-Associated Protein 1LungMiceNF-E2-Related Factor 2PhenotypeTumor MicroenvironmentKEAP1 protein, humanKeap1 protein, mouseKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2immunosuppressionKEAP1lung cancerM2 polarizationmacrophagesNRF2 pathway

Identifiers

PMID38542481
PMCPMC10970780
OpenAlexW4392994039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.