Evidence map›Paper›PMID 38542430›Full record

ArticleInternational journal of molecular sciences2024

Efficient Assessment of Tumor Vascular Shutdown by Photodynamic Therapy on Orthotopic Pancreatic Cancer Using High-Speed Wide-Field Waterproof Galvanometer Scanner Photoacoustic Microscopy.

Jaeyul Lee, Sangyeob Han, Til Bahadur Thapa Magar, Pallavi Gurung, Junsoo Lee, Daewoon Seong, Sungjo Park, Yong-Wan Kim, Mansik Jeon, Jeehyun Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Redox processes in the treatment of advanced skin cancers.Clinical & experimental metastasis · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Phototherapy in cancer treatment: strategies and challenges.Signal transduction and targeted therapy · 2025
    Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jaeyul LeeSchool of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0002-9207-7026
Sangyeob HanSchool of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0002-9440-2478
Til Bahadur Thapa MagarDongsung Cancer Center, Dongsung Bio Pharmaceutical Co., Ltd., Daegu 41061, Republic of Korea.
Pallavi GurungDongsung Cancer Center, Dongsung Bio Pharmaceutical Co., Ltd., Daegu 41061, Republic of Korea.
Junsoo LeeSchool of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0001-8146-6862
Daewoon SeongSchool of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0003-3477-412X
Sungjo ParkLaser Application Center, Institute of Advanced Convergence Technology, Kyungpook National University, Daegu 41061, Republic of Korea.
Yong-Wan KimDongsung Cancer Center, Dongsung Bio Pharmaceutical Co., Ltd., Daegu 41061, Republic of Korea.
Mansik JeonSchool of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu 41566, Republic of Korea.
Jeehyun KimSchool of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0003-1217-9338
Kyungpook National University · KRBio Pharm Dongsung (South Korea) · KR

Funding

Basic Science Research Program through the NRF 2018R1D1A1B07043340Bio & Medical Technology Development Program of the NRF 2017M3A9E2065282BK21 Plus project funded by the Ministry of Education 21A20131600011the Korea Health Technology R&D Project, KHIDI HI21C1266
6 · The paper itself

Abstract

To identify the vascular alteration by photodynamic therapy (PDT), the utilization of high-resolution, high-speed, and wide-field photoacoustic microscopy (PAM) has gained enormous interest. The rapid changes in vasculature during PDT treatment and monitoring of tumor tissue activation in the orthotopic pancreatic cancer model have received limited attention in previous studies. Here, a fully two-axes waterproof galvanometer scanner-based photoacoustic microscopy (WGS-PAM) system was developed for in vivo monitoring of dynamic variations in micro blood vessels due to PDT in an orthotopic pancreatic cancer mouse model. The photosensitizer (PS), Chlorin e6 (Ce6), was utilized to activate antitumor reactions in response to the irradiation of a 660 nm light source. Microvasculatures of angiogenesis tissue were visualized on a 40 mm

Indexed as

ChlorophyllidesPancreatic NeoplasmsPhotochemotherapyPorphyrinsAnimalsCell Line, TumorMiceMicroscopyPhotosensitizing AgentsVascular Endothelial Growth Factor AChlorophyllidesPhotosensitizing AgentsPorphyrinsVascular Endothelial Growth Factor Achlorin e6pancreatic cancerphotoacoustic microscopyphotodynamic therapywaterproof galvanometer scanner

Identifiers

PMID38542430
PMCPMC10970422
OpenAlexW4392953648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.