Evidence map›Paper›PMID 38542410›Full record

ReviewInternational journal of molecular sciences2024

Biomarkers in Contrast-Induced Acute Kidney Injury: Towards A New Perspective.

María Ángeles González-Nicolás, Cristian González-Guerrero, Marian Goicoechea, Lisardo Boscá, Lara Valiño-Rivas, Alberto Lázaro

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07294911 (Predictors of Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndrome), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07294911 completednot on this map

Predictors of Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndrome

TypeobservationalSponsorKaraganda Medical UniversityRan2024 to 2025Enrolled88ConditionsAcute Coronary Syndrome, Contrast-Induced Acute Kidney InjuryArmsObservational data collection
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Molecules (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

María Ángeles González-NicolásRenal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.ORCID 0000-0002-3514-4616
Cristian González-GuerreroRenal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.
Marian GoicoecheaDepartment of Nephrology, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.
Lisardo BoscáInstituto de Investigaciones Biomédicas Alberto Sols-Morreale (CSIC-UAM), 28029 Madrid, Spain.ORCID 0000-0002-0253-5469
Lara Valiño-RivasRenal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.ORCID 0000-0003-3340-0716
Alberto LázaroRenal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.ORCID 0000-0002-1095-679X
Hospital General Universitario Gregorio Marañón · ESInstituto de Investigaciones Biomédicas Sols-Morreale · ESUniversidad Complutense de Madrid · ES

Funding

Comunidad de Madrid CIFRA_COR-CM, grant number 2022/BMD-7223Fundación Mutua Madrileña XX Convocatoria de Ayudas a la Investigación en SaludInstituto de Salud Carlos III CIBERCVInstituto de Salud Carlos III ICI21/00111Instituto de Salud Carlos III PI20/01577Instituto de Salud Carlos III RICORS2040 (Kidney Disease, grant number RD21/0005/0029)
6 · The paper itself

Abstract

Contrast-Induced Acute Kidney Injury (CI-AKI) remains a frequent iatrogenic condition since radiological procedures using intra-vascular iodinated contrast media (CM) are being widely administered for diagnostic and therapeutic purposes. Despite the improvement of the medical healthcare system worldwide, CI-AKI is still associated with direct short-term and indirect long-term outcomes including increased morbidity and mortality, especially in patients with underlying pre-existing renal function impairment, cardiovascular disease, or diabetes that could rapidly progress into Chronic Kidney Disease. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage Kidney Disease), AKIN (Acute Kidney Injury Network), and KDIGO (Kidney Disease Improving Global Outcomes) clinical criteria and recommendation guidelines are based on traditional "gold standard" biomarkers known as serum creatinine, glomerular filtration rate, and urinary output, new reliable serum and urinary biomarkers are still needed for an effective unified diagnostic strategy for AKI. Starting from previous and recent publications on the benefits and limitations of validated biomarkers responding to kidney injury, glomerular filtration, and inflammation among others, this review unravels the role of new emerging biomarkers used alone or in combination as reliable tools for early diagnosis and prognosis of CI-AKI, taking into account patients and procedures-risk factors towards a new clinical perspective.

Indexed as

Acute Kidney InjuryDrug-Related Side Effects and Adverse ReactionsKidney Failure, ChronicBiomarkersCreatinineHumansKidneyRisk FactorsBiomarkersCreatininebiomarkerscontrast-induced acute kidney injurycontrast medianephrotoxicity

Identifiers

PMID38542410
PMCPMC10970772
OpenAlexW4392961216

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.