Evidence map›Paper›PMID 38542393›Full record

ArticleInternational journal of molecular sciences2024

Landscape of FLT3 Variations Associated with Structural and Functional Impact on Acute Myeloid Leukemia: A Computational Study.

Zeenat Mirza, Dalal A Al-Saedi, Nofe Alganmi, Sajjad Karim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Observational
  3. Molecular medicine reports · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zeenat MirzaKing Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-6222-4873
Dalal A Al-SaediDepartment of Biochemistry, Faculty of Sciences, University of Tabuk, Tabuk 48322, Saudi Arabia.ORCID 0000-0003-3105-5517
Nofe AlganmiCenter of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-1219-5592
Sajjad KarimDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-0907-2097
King Abdulaziz University · SAUniversity of Tabuk · SA

Funding

Institutional Fund Projects, Ministry of Education and King Abdulaziz University, Jeddah, Saudi Arabia IFPRC-137-141-2020
6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is hallmarked by the clonal proliferation of myeloid blasts. Mutations that result in the constitutive activation of the fms-like tyrosine kinase 3 (

Indexed as

fms-Like Tyrosine Kinase 3Leukemia, Myeloid, AcuteHumansMolecular Docking SimulationMutationProtein-Tyrosine KinasesSorafenibFLT3 protein, humanfms-Like Tyrosine Kinase 3Protein-Tyrosine KinasesSorafenibacute myeloid leukemiaannotationFLT3I836predictionsorafenibvariant

Identifiers

PMID38542393
PMCPMC10970727
OpenAlexW4392897358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.