Evidence map›Paper›PMID 38542321›Full record

ArticleInternational journal of molecular sciences2024

Topical Neuropeptide Y for Ischemic Skin Wounds.

Tais Stangerup, Lise Mette Rahbek Gjerdrum, Michael Bzorek, Line Andersen, Anne-Marie Heegaard, Lars N Jorgensen, Magnus S Ågren

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tais StangerupDigestive Disease Center, Bispebjerg Hospital, University of Copenhagen, 2400 Copenhagen, Denmark.
Lise Mette Rahbek GjerdrumDepartment of Pathology, Zealand University Hospital, 4000 Roskilde, Denmark.ORCID 0000-0003-4377-3209
Michael BzorekDepartment of Pathology, Zealand University Hospital, 4000 Roskilde, Denmark.
Line AndersenDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
Anne-Marie HeegaardDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
Lars N JorgensenDigestive Disease Center, Bispebjerg Hospital, University of Copenhagen, 2400 Copenhagen, Denmark.ORCID 0000-0001-7465-5374
Magnus S ÅgrenDigestive Disease Center, Bispebjerg Hospital, University of Copenhagen, 2400 Copenhagen, Denmark.ORCID 0000-0002-2263-0826
University of Copenhagen · DKZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective was to investigate the effects of topically applied neuropeptide Y (NPY) on ischemic wounds. Initially, the animal model for ischemic wound healing was validated using 16 male Sprague Dawley albino rats. In the intervention study, an additional 28 rats were divided into three groups: NPY (0.025%), the positive control insulin-like growth factor-I (IGF-I, 0.0025%), and the hydrogel carrier alone (control). The hydrogel was selected due to its capacity to prolong NPY release (

Indexed as

Neuropeptide YWound HealingAnimalsHydrogelsMaleRatsRats, Sprague-DawleyReceptors, Neuropeptide YHydrogelsNeuropeptide YReceptors, Neuropeptide Ygrowth factorsneuropeptidesrelease diffusion model

Identifiers

PMID38542321
PMCPMC10970629
OpenAlexW4392847411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.