Evidence map›Paper›PMID 38542259›Full record

ArticleInternational journal of molecular sciences2024

Undifferentiated Carcinoma with Osteoclast-like Giant Cells of the Pancreas: Molecular Genetic Analysis of 13 Cases.

Jan Hrudka, Markéta Kalinová, Vanda Ciprová, Jana Moravcová, Radim Dvořák, Radoslav Matěj

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jan HrudkaDepartment of Pathology, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, 100 34 Prague, Czech Republic.ORCID 0000-0002-5649-4586
Markéta KalinováDepartment of Pathology, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, 100 34 Prague, Czech Republic.
Vanda CiprováDepartment of Pathology, 1st Faculty of Medicine, Charles University, General University Hospital, 128 00 Prague, Czech Republic.
Jana MoravcováDepartment of Pathology, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, 100 34 Prague, Czech Republic.
Radim DvořákDepartment of General Surgery, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, 100 34 Prague, Czech Republic.
Radoslav MatějDepartment of Pathology, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, 100 34 Prague, Czech Republic.ORCID 0000-0002-6152-6343
Charles University · CZ

Funding

Charles University Cooperatio Medical Diagnostics
6 · The paper itself

Abstract

Undifferentiated carcinoma with osteoclast-like giant cells (UCOGC) of the pancreas is a rare malignancy regarded as a subvariant of pancreatic ductal carcinoma (PDAC) characterized by variable prognosis. UCOGC shows a strikingly similar spectrum of oncogenic DNA mutations to PDAC. In the current work, we analyzed the landscape of somatic mutations in a set of 13 UCOGC cases via next-generation sequencing (NGS). We detected a spectrum of pathogenic or likely pathogenic mutations similar to those observed in PDAC following previously published results (10

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsGiant CellsHumansMolecular BiologyMutationOsteoclastsPancreasDNAnext-generation sequencingpancreasundifferentiated carcinoma with osteoclast-like giant cells

Identifiers

PMID38542259
PMCPMC10970188
OpenAlexW4392810679

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.