Evidence map›Paper›PMID 38542238›Full record

ReviewInternational journal of molecular sciences2024

Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases.

Adele Muscolo, Oliva Mariateresa, Torello Giulio, Russo Mariateresa

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07505212 (Exploring Tannin-Probiotic Interactions on Microbial Composition and Inflammatory Outcomes in Obesity), which is not on this map. Cited by 167 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07505212 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Exploring Tannin-Probiotic Interactions on Microbial Composition and Inflammatory Outcomes in Obesity

TypeinterventionalSponsorPrairie View A&M UniversityRan2026 to 2026Enrolled20ConditionsObesity (Disorder)ArmsGallotannin-rich mango, Lactiplantibacillus pentosus (probiotic), No Treatment Added
3 · Its place in the literature

Who cites it

167 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  18. Acute Effects ofFoods (Basel, Switzerland) · 2026
    Article
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107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adele MuscoloDepartment of AGRARIA, "Mediterranea" University, Feo di Vito, 89124 Reggio Calabria, Italy.ORCID 0000-0002-0439-1614
Oliva MariateresaDepartment of AGRARIA, "Mediterranea" University, Feo di Vito, 89124 Reggio Calabria, Italy.ORCID 0009-0009-5846-6050
Torello GiulioTL Pharma Via Lago di Martignano, 18, 65129 Pescara, Italy.ORCID 0009-0007-7289-513X
Russo MariateresaDepartment of AGRARIA, "Mediterranea" University, Feo di Vito, 89124 Reggio Calabria, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress, characterized by an imbalance favouring oxidants over antioxidants, is a key contributor to the development of various common diseases. Counteracting these oxidants is considered an effective strategy to mitigate the levels of oxidative stress in organisms. Numerous studies have indicated an inverse correlation between the consumption of vegetables and fruits and the risk of chronic diseases, attributing these health benefits to the presence of antioxidant phytochemicals in these foods. Phytochemicals, present in a wide range of foods and medicinal plants, play a pivotal role in preventing and treating chronic diseases induced by oxidative stress by working as antioxidants. These compounds exhibit potent antioxidant, anti-inflammatory, anti-aging, anticancer, and protective properties against cardiovascular diseases, diabetes mellitus, obesity, and neurodegenerative conditions. This comprehensive review delves into the significance of these compounds in averting and managing chronic diseases, elucidating the key sources of these invaluable elements. Additionally, it provides a summary of recent advancements in understanding the health benefits associated with antioxidant phytochemicals.

Indexed as

AntioxidantsOxidative StressChronic DiseaseHumansOxidantsPhytochemicalsAntioxidantsOxidantsPhytochemicalsantioxidant phytochemicalschronic diseasefree radicalshealth benefitspolyphenols

Identifiers

PMID38542238
PMCPMC10970659

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.