Evidence map›Paper›PMID 38542212›Full record

ArticleInternational journal of molecular sciences2024

Genetic Background of Acute Heart Rate Response to Exercise.

Péter Pikó, Habib Al Ashkar, Nóra Kovács, Ilona Veres-Balajti, Róza Ádány

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Association ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Péter PikóDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0001-5539-907X
Habib Al AshkarHUN-REN-UD Public Health Research Group, Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Nóra KovácsDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0001-9256-3756
Ilona Veres-BalajtiDepartment of Physiotherapy, Faculty of Health Sciences, Institute of Health Sciences, University of Debrecen, 4028 Debrecen, Hungary.
Róza ÁdányDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-9679-6669
University of Debrecen · HUSemmelweis University · HU

Funding

European Regional Development Fund GINOP-2.3.2-15-2016-00005Hungarian Academy of Sciences TK2016-78Hungarian Research Network TKCS-2021/32Janos Bolyai Research Scholarship BO/00513/23/5National Research, Development, and Innovation Fund of Hungary Project No. 135784National Research, Development, and Innovation Fund of Hungary ÚNKP-23-5-DE-494National Research, Development and Innovation Office RRF-2.3.1-21-2022-00006
6 · The paper itself

Abstract

The acute heart rate response (AHRR) to physical activity, which refers to the change in heart rate during and after exercise, has been associated with cardiovascular and all-cause mortality. Previous studies have shown that AHRR is significantly determined by genetics in addition to environmental and lifestyle factors. The aim of this study was to investigate the genetic background of AHRR by analysing ten single nucleotide polymorphisms (SNPs) associated with leisure-time physical activity (LTPA) in 620 samples from the Hungarian population. The AHRR can be characterised as the difference between post-exercise and resting heart rate, i.e., the delta heart rate (ΔHR) defined by the YMCA 3 min step test, with a lower value indicating better cardiovascular fitness. The association of SNPs with ΔHR was analysed both separately and in combination using an optimised polygenic score (oPGS). The results showed that five SNPs (rs10252228, rs459465, rs6022999, rs8097348, and rs12405556) had at least nominally significant (

Indexed as

ExerciseMotor ActivityGenetic BackgroundHeart Rateacute heart rate responsecardiorespiratory fitnessleisure-time physical activityoptimised polygenic scoresingle nucleotide polymorphismYMCA 3 min step test

Identifiers

PMID38542212
PMCPMC10970476
OpenAlexW4392752826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.