ArticleInternational journal of molecular sciences2024
Healing of Skin Wounds in Rats Using Creams Based on Symphytum Officinale Extract.
Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 6 citations in OpenAlex.
- Anti-Inflammatory and Antimicrobial Activities of Extracts Developed fromInternational journal of molecular sciences · 2026Article
- Organ-Specific Phytochemical Profiles, Wound-Healing and Hemostatic Activities ofMolecules (Basel, Switzerland) · 2026Article
- Skin Regeneration in Diabetic Rats Using Gold Nanoparticles-Bioactive Glass Oil-in-Water Cream.Materials (Basel, Switzerland) · 2026Article
- Integrative Therapies in Wound Healing in Small Animals: An Approach Beyond Traditional Medicine.Veterinary sciences · 2026Review
- Wound healing potential of methanolic extract of Wrightia tinctoria fresh leaf.Die Naturwissenschaften · 2026Article
- Ethnopharmacological insights intoFrontiers in pharmacology · 2026Review
- Plant-derived modulators of the hemostasis-wound healing axis: mechanisms, evidence, and translational potential.Frontiers in pharmacology · 2026Review
- Wound Healing Effects of New Cream Formulations with Herbal Ingredients.Pharmaceutics · 2025Article
- The Potential of Composite Cements for Wound Healing in Rats.Bioengineering (Basel, Switzerland) · 2024Article
- Assessing Biocompatibility of Composite Cements by Peri/Intramuscular and Subcutaneous Implantation in Rats.Biomedicines · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
Abstract
Rosmarinic acid is a well-known natural antioxidant and anti-inflammatory compound, and it is one of the polyphenolic compounds found in comfrey plants. Comfrey root also contains allantoin, which helps with new skin regeneration. This study aimed to investigate the healing and skin regeneration process of skin wounds in Wistar rats using creams based on comfrey extract and to correlate the results with active compounds in the extract. The obtained results showed that comfrey root is rich in bioactive compounds, including allantoin, salvianolic acid, and rosmarinic acid, which are known for their great free radical scavenging activity, and the high antioxidant activity of the extract may be mainly due to these compounds. The obtained extract has an antimicrobial effect on
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.