Evidence map›Paper›PMID 38541988›Full record

ReviewJournal of clinical medicine2024

Pseudodementia in Patients with Unipolar and Bipolar Disorders: A Case Series and Literature Review.

Camilla Elefante, Giulio Emilio Brancati, Donatella Acierno, Gabriele Pistolesi, Sara Ricciardulli, Francesco Weiss, Francesca Romeo, Lorenzo Lattanzi, Icro Maremmani, Giulio Perugi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Guideline
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Camilla ElefantePsychiatry Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-3865-7975
Giulio Emilio BrancatiPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-4460-0406
Donatella AciernoPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Gabriele PistolesiPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Sara RicciardulliPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Francesco WeissPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Francesca RomeoPsychiatric Unit, NHS Cuneo Unit 1, 12100 Cuneo, Italy.
Lorenzo LattanziPsychiatric Unit, Santa Chiara University Hospital, 56126 Pisa, Italy.
Icro MaremmaniPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-6324-0576
Giulio PerugiPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-5556-1858
University of Pisa · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITOspedale Santa Chiara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Even though pseudodementia has been historically linked to depression, other psychiatric conditions may cause reversible cognitive alterations. The purpose of this study is to improve our understanding of pseudodementia occurring throughout the entire bipolar spectrum. A systematic review was conducted according to PRISMA guidelines. PubMed, Scopus, and Web of Science databases were searched up to March 2023. Fifteen articles on patients with pseudodementia and bipolar disorder (BD), mania, hypomania, or mixed depression have been included. Moreover, seven female patients with mood disorders diagnosed with pseudodementia have been described. According to our research, pseudodementia in patients with BD mostly occurs during a depressive episode. However, pseudodementia has also been observed in the context of manic and mixed states. Psychomotor and psychotic symptoms were commonly associated. The most typical cognitive impairments were disorientation, inattention, and short-term memory deficits. Alterations in neuroimaging were frequently observed. Electroconvulsive therapy and lithium, either alone or in combination with antipsychotics, resulted in the most widely used therapies. Cognitive decline may occur in a substantial proportion of patients. Since pseudodementia can manifest along the entire mood spectrum, it should be taken into consideration as a possible diagnosis in BD patients showing cognitive deficits during manic, mixed, and depressive states.

Indexed as

bipolar disorderbipolar spectrumcognitive reservedepressive pseudodementiamanic pseudodementiamood spectrumneurodegenerationpredementiapseudodementiareversible dementia

Identifiers

PMID38541988
PMCPMC10971625
OpenAlexW4392949744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.