Evidence map›Paper›PMID 38541936›Full record

ReviewJournal of clinical medicine2024

The Impact of Antimicrobial Resistance in Cystic Fibrosis.

Antonio Vitiello, Francesco Blasi, Michela Sabbatucci, Andrea Zovi, Francesco Miele, Annarita Ponzo, Roberto Langella, Mariarosaria Boccellino

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Probiotics and postbiotics to counter antimicrobial resistant infections, an editorial.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  5. Article
  6. HuR-Targeted Small Molecules ReduceInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Insights on the Pathogenesis ofJournal of clinical medicine · 2025
    Review
  12. Article
  13. Menadione as Antibiotic Adjuvant AgainstAntibiotics (Basel, Switzerland) · 2025
    Article
  14. The importance of antibiotic treatment duration in antimicrobial resistance.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Antonio VitielloMinistry of Health, Viale Giorgio Ribotta 5, 00144 Rome, Italy.ORCID 0000-0003-2623-166X
Francesco BlasiRespiratory Unit and Cystic Fibrosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-2285-9970
Michela SabbatucciDepartment Infectious Diseases, Italian National Institute of Health, 00161 Rome, Italy.ORCID 0000-0001-5889-1780
Andrea ZoviMinistry of Health, Viale Giorgio Ribotta 5, 00144 Rome, Italy.ORCID 0000-0002-6528-2171
Francesco MieleGeneral Surgery Unit, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0009-0008-7368-258X
Annarita PonzoBiology Department, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-6190-0753
Roberto LangellaItalian Society of Hospital Pharmacy (SIFO), SIFO Secretariat of the Lombardy Region, Carlo Farini Street 81, 20159 Milan, Italy.
Mariarosaria BoccellinoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", 81100 Naples, Italy.ORCID 0000-0001-6989-010X
Ministero della Salute · ITUniversity of Campania "Luigi Vanvitelli" · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITRegione LombardiaUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phenomenon of antimicrobial resistance (AMR) is a critical global health challenge, with prospects indicating its potential to become the leading cause of death worldwide in the coming years. Individuals with pre-existing conditions, such as neoplastic disease undergoing chemotherapy, those on immunosuppressive therapy, and individuals with rare diseases like cystic fibrosis (CF), face heightened challenges due to AMR. CF is a rare disease caused by a deficiency in the synthesis of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) channel protein, resulting in multi-organ clinical symptoms, particularly in the respiratory system. PwCF experience recurrent pulmonary exacerbations triggered by bacterial or viral infections, making them particularly vulnerable to the impact of AMR. This review delves into the complex relationship between AMR and climate dynamics, focusing on the unique challenges faced by individuals with CF. It discusses the methods employed to measure AMR, its global impact on antibiotic resistance, and the specific microbial communities present in the CF airway. The review also explores the intricacies of antimicrobial resistance within the context of cystic fibrosis, emphasizing the urgent need for research in this field.

Indexed as

antimicrobial resistance (AMR)CFTR channelcystic fibrosismicrobial communitiespulmonary exacerbations

Identifiers

PMID38541936
PMCPMC10970943
OpenAlexW4392915956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.