Evidence map›Paper›PMID 38541904›Full record

ArticleJournal of clinical medicine2024

The Difficulty of Detecting Occult Metastases in Patients with Potentially Resectable Pancreatic Cancer: Development and External Validation of a Preoperative Prediction Model.

Marieke Walma, Laura Maggino, F Jasmijn Smits, Alicia S Borggreve, Lois A Daamen, Vincent P Groot, Fabio Casciani, Vincent E de Meijer, Frank J Wessels, George P van der Schelling and 20 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Marieke WalmaDepartment of Surgery, Regional Academic Cancer Center Utrecht, University Medical Center Utrecht and St. Antonius Hospital, University Utrecht, 3508 GA Utrecht, The Netherlands.
Laura MagginoThe Pancreas Institute, University of Verona Hospital Trust, 37134 Verona, Italy.
F Jasmijn SmitsDepartment of Surgery, Regional Academic Cancer Center Utrecht, University Medical Center Utrecht and St. Antonius Hospital, University Utrecht, 3508 GA Utrecht, The Netherlands.
Alicia S BorggreveDepartment of Surgery, Regional Academic Cancer Center Utrecht, University Medical Center Utrecht and St. Antonius Hospital, University Utrecht, 3508 GA Utrecht, The Netherlands.
Lois A DaamenDepartment of Surgery, Regional Academic Cancer Center Utrecht, University Medical Center Utrecht and St. Antonius Hospital, University Utrecht, 3508 GA Utrecht, The Netherlands.
Vincent P GrootDepartment of Surgery, Regional Academic Cancer Center Utrecht, University Medical Center Utrecht and St. Antonius Hospital, University Utrecht, 3508 GA Utrecht, The Netherlands.
Fabio CascianiThe Pancreas Institute, University of Verona Hospital Trust, 37134 Verona, Italy.ORCID 0000-0001-8225-2399
Vincent E de MeijerDepartment of Surgery, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-7900-5917
Frank J WesselsDepartment of Radiology, Regional Academic Cancer Center Utrecht, University Medical Center Utrecht and St. Antonius Hospital, University Utrecht, 3508 GA Utrecht, The Netherlands.
George P van der SchellingDepartment of Surgery, Amphia Hospital Breda, 4818 CK Breda, The Netherlands.
Vincent B NieuwenhuijsDepartment of Surgery, Isala Hospital, 8025 AB Zwolle, The Netherlands.
Koop BosschaDepartment of Surgery, Jeroen Bosch Hospital, 5223 GZ 's-Hertogenbosch, The Netherlands.
Erwin van der HarstDepartment of Surgery, Maasstad Hospital, 3079 DZ Rotterdam, The Netherlands.
Ronald van DamDepartment of Surgery, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.
Mike S LiemDepartment of Surgery, Medical Spectrum Twente, 7511 HN Enschede, The Netherlands.
Sebastiaan FestenDepartment of Surgery, Onze Lieve Vrouwe Gasthuis, 1091 AC Amsterdam, The Netherlands.
Martijn W J StommelDepartment of Surgery, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Daphne RoosDepartment of Surgery, Reiner de Graaf Hospital, 2625 AD Delft, The Netherlands.
Fennie WitDepartment of Surgery, Tjongerschans Hospital, 8441 PW Heerenveen, The Netherlands.
Ignace H de HinghDepartment of Surgery, Catharina Hospital, 5623 EJ Eindhoven, The Netherlands.
Bert A BonsingDepartment of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Olivier R BuschDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Bas Groot KoerkampDepartment of Surgery, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands.
Geert KazemierDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Marc G BesselinkDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Roberto SalviaThe Pancreas Institute, University of Verona Hospital Trust, 37134 Verona, Italy.ORCID 0000-0002-3514-8473
Giuseppe MalleoThe Pancreas Institute, University of Verona Hospital Trust, 37134 Verona, Italy.ORCID 0000-0001-5467-2628
I Quintus MolenaarDepartment of Surgery, Regional Academic Cancer Center Utrecht, University Medical Center Utrecht and St. Antonius Hospital, University Utrecht, 3508 GA Utrecht, The Netherlands.
Hjalmar C van SantvoortDepartment of Surgery, Regional Academic Cancer Center Utrecht, University Medical Center Utrecht and St. Antonius Hospital, University Utrecht, 3508 GA Utrecht, The Netherlands.
Dutch Pancreatic Cancer Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occult metastases are detected in 10-15% of patients during exploratory laparotomy for pancreatic cancer. This study developed and externally validated a model to predict occult metastases in patients with potentially resectable pancreatic cancer. Model development was performed within the Dutch Pancreatic Cancer Audit, including all patients operated for pancreatic cancer (January 2013-December 2017). Multivariable logistic regression analysis based on the Akaike Information Criteria was performed with intraoperative pathologically proven metastases as the outcome. The model was externally validated with a cohort from the University Hospital of Verona (January 2013-December 2017). For model development, 2262 patients were included of whom 235 (10%) had occult metastases, located in the liver (

Indexed as

occult metastasespancreatic cancerprediction model

Identifiers

PMID38541904
PMCPMC10971241

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.