Evidence map›Paper›PMID 38541700›Full record

ArticleLife (Basel, Switzerland)2024

In Vitro Study of Interleukin-6 when Used at Low Dose and Ultra-Low Dose in Micro-Immunotherapy.

Camille Jacques, Flora Marchand, Mathias Chatelais, Adrien Brulefert, Mathieu Riffault, Ilaria Floris

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Active Substances from the Micro-Immunotherapy Medicine 2LC1International journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camille JacquesPreclinical Research Department, Labo'Life France, Pescalis-Les Magnys, 79320 Moncoutant-sur-Sevre, France.ORCID 0000-0002-8044-0545
Flora MarchandProfileHIT, 7 rue du Buisson, 44680 Sainte-Pazanne, France.
Mathias ChatelaisProfileHIT, 7 rue du Buisson, 44680 Sainte-Pazanne, France.
Adrien BrulefertQIMA Life Sciences, 1 bis rue des Plantes-CS 50011-86160, 44680 Gençay, France.
Mathieu RiffaultAtlantic Bone Screen (ABS), 3 rue Aronnax, 44800 Saint-Herblain, France.
Ilaria FlorisPreclinical Research Department, Labo'Life France, Pescalis-Les Magnys, 79320 Moncoutant-sur-Sevre, France.ORCID 0000-0003-4089-3133

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As one of the major cytokines implicated in the orchestration of immune responses, interleukin 6 (IL-6) can either act as a pro- or an anti-inflammatory factor, depending on the micro-environment. In micro-immunotherapy (MI) medicines, IL-6 is employed at low doses (LD) and ultra-low doses (ULD), expressed in centesimal Hahnemannian (CH), and used alone or in combination with other immune regulators to modulate patients' immune responses. The present study focused on assessing the in vitro immune-modulatory effects of two IL-6-containing MI products: (i) the unitary IL-6 (4 CH) and (ii) the complex MI-medicine (MIM) 2LALERG

Indexed as

allergyimmune cells modelsimmune responses modulationinterleukin-6low dosesmicro-immunotherapyultra-low doses

Identifiers

PMID38541700
PMCPMC10971188
OpenAlexW4392715959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.