Localised Electrochemical Impedance Spectroscopy of Gold Nanoparticles Labelled Antibodies Probed by Platinum Microstructured Ultramicroelectrode.

Antanas Zinovicius, Inga Morkvenaite-Vilkonciene, Arunas Ramanavicius

Abstract read

In one paragraph

Article in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Antanas ZinoviciusDepartment of Mechatronics, Robotics and Digital Manufacturing, Vilnius Gediminas Technical University, 10105 Vilnius, Lithuania.ORCID 0000-0003-0865-5880

Inga Morkvenaite-VilkoncieneDepartment of Nanotechnology, State Research Institute Centre for Physical Sciences and Technology, 02300 Vilnius, Lithuania.ORCID 0000-0001-5936-9900

Arunas RamanaviciusDepartment of Nanotechnology, State Research Institute Centre for Physical Sciences and Technology, 02300 Vilnius, Lithuania.ORCID 0000-0002-0885-3556

Funding

Lietuvos Mokslo Taryba S-MIP-22-87

6 · The paper itself

Abstract

This research is focused on enhancing the capabilities of scanning electrochemical impedance microscopy (SEIM) for detecting gold nanoparticle-labelled antibodies using electrochemically modified platinum ultramicroelectrode. The primary objective was to address the high resistance issue encountered in previous measurements with SEIM via the utilization of SEIM probes based on micro-electrodes modified by platinum microstructures, which improved the sensitivity and precision of the detection of targeted biomolecules. The modified probe resulted in a lowered charge transfer resistance by over ten times and a decrease in detection to around 100 fg/mL. We suggest potential applications in various biotechnological and biomedical fields, with future research expected to further refine this technique.

Indexed as

electrochemical immunosensorelectrode modificationreusable transducerscanning electrochemical impedance microscopySEIMtransducerultramicroelectrode

Identifiers

PMID38541493

DOI10.3390/ma17061339

PMCPMC10971954

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.