Evidence map›Paper›PMID 38540987›Full record

ArticleJournal of personalized medicine2024

Efficacity and Safety of the Fluocinolone Acetonide Implant in Uveitic Macular Edema: A Real-Life Study from the French Uveitis Network.

Matthieu Jabbour, Laurent Kodjikian, Alexandre Bourdin, Marie-Bénédicte Rougier, Yasmine Serrar, Michel Weber, Hélène Massé, Driss Mazhar, Sara Perez-Roustit, Christophe Chiquet and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Recurrent uveitic macular edema managed with intravitreal faricimab injection.Journal of ophthalmic inflammation and infection · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Matthieu JabbourDepartment of Ophthalmology, Pitié Salpêtrière University Hospital, Sorbonne University, 75013 Paris, France.
Laurent KodjikianDepartment of Ophthalmology, Hôpital Universitaire de la Croix-Rousse, Hospices Civils de Lyon, University Claude Bernard Lyon 1, 69004 Lyon, France.ORCID 0000-0002-3908-6716
Alexandre BourdinDepartment of Ophthalmology, Pitié Salpêtrière University Hospital, Sorbonne University, 75013 Paris, France.ORCID 0009-0007-2995-4579
Marie-Bénédicte RougierCHU Bordeaux, Service d'Ophtalmologie, 33000 Bordeaux, France.ORCID 0000-0002-0900-7941
Yasmine SerrarDepartment of Ophthalmology, Hôpital Universitaire de la Croix-Rousse, Hospices Civils de Lyon, University Claude Bernard Lyon 1, 69004 Lyon, France.
Michel WeberCHU Nantes, Service d'Ophtalmologie, Nantes University, 1 Place Alexis Ricordeau, 44093 Nantes, France.
Hélène MasséCHU Nantes, Service d'Ophtalmologie, Nantes University, 1 Place Alexis Ricordeau, 44093 Nantes, France.
Driss MazharCHU Nantes, Service d'Ophtalmologie, Nantes University, 1 Place Alexis Ricordeau, 44093 Nantes, France.ORCID 0000-0003-0370-2238
Sara Perez-RoustitDepartment of Ophthalmology, Grenoble Alpes University, 38043 Grenoble, France.
Christophe ChiquetDepartment of Ophthalmology, Grenoble Alpes University, 38043 Grenoble, France.ORCID 0000-0002-7601-4885
Marie Nöelle DelyferCHU Bordeaux, Service d'Ophtalmologie, 33000 Bordeaux, France.ORCID 0000-0002-3127-8617
Bahram BodaghiDepartment of Ophthalmology, Pitié Salpêtrière University Hospital, Sorbonne University, 75013 Paris, France.
Sara TouhamiDepartment of Ophthalmology, Pitié Salpêtrière University Hospital, Sorbonne University, 75013 Paris, France.ORCID 0000-0001-8346-3067
Sorbonne Université · FRNantes Université · FRCentre Hospitalier Universitaire de Bordeaux · FRUniversité Claude Bernard Lyon 1 · FRInserm · FRUniversité Grenoble Alpes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the safety and efficacy of the fluocinolone acetonide implant (FAi, Iluvien

methodsThis retrospective, multicenter real-life study included patients with chronic non-infectious UME who received intravitreal FAi after at least two dexamethasone implants (DEXi).

resultsTwenty-six eyes from 22 patients (73.1% of females) were included. The mean age was 60.4 ± 16 years. The mean follow-up was 11.4 ± 2 months. The mean baseline best-corrected visual acuity (BCVA) was 0.43 ± 0.36 LogMAR, improving significantly after 1, 3, 6 and 12 months (all

conclusionFAi implantation led to a significant BCVA and CMT improvement with a good safety profile over the 12-month follow-up. Predictive factors of treatment outcomes seem to include the anatomical response to DEXi and the presence of DRIL and HRF at baseline.

Indexed as

chronic non-infectious uveitisdexamethasoneDRILfluocinolone acetonide implanthyperreflective focipredictive factoruveitic macular edema

Identifiers

PMID38540987
PMCPMC10971732
OpenAlexW4392166260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.