Evidence map›Paper›PMID 38540765›Full record

ArticleBiomolecules2024

Phosphatase and Tensin Homolog Inhibition in Proteolipid Protein 1-Expressing Cells Stimulates Neurogenesis and Gliogenesis in the Postnatal Enteric Nervous System.

Crystal Woods, Amanda R Flockton, Jaime Belkind-Gerson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. The Physiology of Enteric Glia.Annual review of physiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Crystal WoodsDepartment of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO 80045, USA.ORCID 0000-0001-7112-6215
Amanda R FlocktonDepartment of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO 80045, USA.
Jaime Belkind-GersonDepartment of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO 80045, USA.
University of Colorado Anschutz Medical Campus · USChildren's Hospital Colorado · US

Funding

Defining the Role of Enteric Nervous System Dysfunction in Gastrointestinal Motor and Sensory Abnormalities in Down SyndromeRF1NS128738 · NINDS · UNIVERSITY OF COLORADO DENVER · PI BELKIND-GERSON, JAIME, FRANK, DANIEL N · 2023 to 2023
$2.8M
Schwann Cell-derived neuro-gliogenesisR01DK134561 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Jaime Belkind-gerson, Daniel N Frank · 2023 to 2026
$2.3M
Department of Pediatrics at the University of Colorado N/ADigestive Health Institute at Children's Hospital Colorado Academic Enrichment Fund N/ANIDDK NIH HHS R01 DK134561NINDS NIH HHS RF1 NS128738
6 · The paper itself

Abstract

Phosphatase and tensin homolog (Pten) is a key regulator of cell proliferation and a potential target to stimulate postnatal enteric neuro- and/or gliogenesis. To investigate this, we generated two tamoxifen-inducible Cre recombinase murine models in which

Indexed as

Enteric Nervous SystemAnimalsCalbindin 2MiceNeurogenesisProteolipidsTamoxifenTensinsCalb2 protein, mouseCalbindin 2ProteolipidsTamoxifenTensinsCalb2enteric gliaenteric nervous systementeric neuronsgastrointestinal motilityPlp1Ptenshort-bowel syndrome

Identifiers

PMID38540765
PMCPMC10967813
OpenAlexW4392742026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.