Evidence map›Paper›PMID 38540227›Full record

ArticleBiomedicines2024

MSR405: Inhibiting Neuroinflammation after Spinal Cord Injury in Rats.

Yu Liu, Yu Xiao, Jimeng Gao, Jiaxin Gao, Ruicheng Li, Zhongquan Qi, Xiaocun Liu

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu LiuMedical College, Guangxi University, Nanning 530004, China.
Yu XiaoMedical College, Guangxi University, Nanning 530004, China.
Jimeng GaoMedical College, Guangxi University, Nanning 530004, China.
Jiaxin GaoMedical College, Guangxi University, Nanning 530004, China.
Ruicheng LiMedical College, Guangxi University, Nanning 530004, China.
Zhongquan QiMedical College, Guangxi University, Nanning 530004, China.
Xiaocun LiuXiang'an Hospital of Xiamen University, Xiamen 361005, China.

Funding

National Natural Science Foundation of China 81771721 and 81971505
6 · The paper itself

Abstract

The treatment of spinal cord injury (SCI) is often ineffective. Additionally, SCI-induced inflammation leads to secondary injury. Current anti-inflammatory hydrophilic drugs fail to reach the nerve injury site due to the blood-brain barrier. Here, we synthesized MSR405, a new lipophilic unsaturated fatty acid derivative of

Indexed as

anti-inflammationMSR405NF-κBRadix IsatidisSCI

Identifiers

PMID38540227
PMCPMC10968230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.