Evidence map›Paper›PMID 38540206›Full record

ReviewBiomedicines2024

Predictive Value and Therapeutic Significance of Somatic BRCA Mutation in Solid Tumors.

Gyongyver Szentmartoni, Dorottya Mühl, Renata Csanda, Attila Marcell Szasz, Zoltan Herold, Magdolna Dank

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. SEOM-GEICAM-SOLTI clinical guidelines in advanced breast cancer (UPDATE 2025).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Guideline
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Role of PARP Inhibitors: A New Hope for Breast Cancer Therapy.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Review
  9. Precision therapy in metastatic breast cancer: the current landscape of molecular alteration-based therapies.Translational breast cancer research : a journal focusing on translational research in breast cancer · 2025
    Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gyongyver SzentmartoniDivision of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, 1083 Budapest, Hungary.
Dorottya MühlDivision of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, 1083 Budapest, Hungary.
Renata CsandaDivision of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, 1083 Budapest, Hungary.
Attila Marcell SzaszDivision of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, 1083 Budapest, Hungary.ORCID 0000-0003-2739-4196
Zoltan HeroldDivision of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, 1083 Budapest, Hungary.ORCID 0000-0001-5990-4889
Magdolna DankDivision of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, 1083 Budapest, Hungary.ORCID 0000-0002-4694-3624
Semmelweis University · HU

Funding

Semmelweis University APC coverage
6 · The paper itself

Abstract

Ten percent of patients with breast cancer, and probably somewhat more in patients with ovarian cancer, have inherited germline DNA mutations in the breast and ovarian cancer genes

Indexed as

breast neoplasmsovarian neoplasmspancreatic neoplasmsPARP inhibitionprostatic neoplasmssomatic BRCA1/2

Identifiers

PMID38540206
PMCPMC10967875
OpenAlexW4392560878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.