Evidence map›Paper›PMID 38540118›Full record

ArticleBiomedicines2024

An In Silico and In Vitro Assessment of the Neurotoxicity of Mefloquine.

Basma M El Sharazly, Abrar Ahmed, Hany M Elsheikha, Wayne G Carter

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Basma M El SharazlyParasitology Department, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0000-0003-2126-6185
Abrar AhmedFaculty of Pharmacy, Punjab University College of Pharmacy, University of the Punjab, Lahore 54590, Pakistan.
Hany M ElsheikhaSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington LE12 5RD, UK.ORCID 0000-0003-3303-930X
Wayne G CarterClinical Toxicology Research Group, School of Medicine, Royal Derby Hospital Centre, University of Nottingham, Derby DE22 3DT, UK.ORCID 0000-0003-1475-2476
University of Nottingham · GBUniversity of the Punjab · PK

Funding

British Council Egypt British Council Newton-Mosharafa Joint Supervision PhD Scholarship NMJ10/21
6 · The paper itself

Abstract

Mefloquine (MQ) is a quinoline-based anti-malarial drug used for chemoprophylaxis or as a treatment in combination with artesunate. Although MQ has clear anti-

Indexed as

antimalarial drugcholinesterase inhibitormefloquineneurotoxicityredox stress

Identifiers

PMID38540118
PMCPMC10968448
OpenAlexW4392110808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.