Evidence map›Paper›PMID 38539910›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Bioactive Lignan Honokiol Alleviates Ovarian Oxidative Stress in Aging Laying Chickens by Regulating SIRT3/AMPK Pathway.

Yiqiu Chen, Zhaoyu Yang, Jingchun Bai, Xinyu Wang, Qiongyu Yuan, Yuling Mi, Caiqiao Zhang

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yiqiu ChenDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0001-1919-789X
Zhaoyu YangDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Jingchun BaiDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Xinyu WangDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Qiongyu YuanDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Yuling MiDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Caiqiao ZhangDepartment of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-3519-9457
Zhejiang University · CN

Funding

National Natural Science Foundation of China 31972635National Natural Science Foundation of China 32272950
6 · The paper itself

Abstract

Aging is not only a key internal cause of age-related diseases in humans but also poses a threat to the productivity of farm animals with longer breeding cycles, such as laying chickens. Various measures were taken to prolong the laying period by reducing oxidative stress to improve poultry ovarian functions. Within the mitochondria, SIRT3, a member of the Sirtuin family, plays an important role in post-translational modifications and the regulation of protein activities involved in energy metabolism and oxidative response. This study aimed to investigate the alleviating effect of a bioactive lignan Honokiol (HKL) on oxidative stress in aging chicken ovaries in order to retard decline in egg production. The results showed that HKL treatment restored the abnormal balance between cell proliferation and apoptosis, and it enhanced the antioxidant capacity of the H

Indexed as

AMPKchickenHonokiolovarian agingoxidative stressSirtuins

Identifiers

PMID38539910
PMCPMC10967992
OpenAlexW4393004789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.