Evidence map›Paper›PMID 38539903›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Se Alleviated Pb-Caused Neurotoxicity in Chickens:

Yansheng Li, Jiatian Liang, Chunyu Jiang, Jiawen Cui, Lan Hong, Zhiyu Hao, You Tang, Yuhao Liu, Xun Cui, Xiaohua Teng

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yansheng LiCollege of Medicine, Yanbian University, Yanji 133002, China.
Jiatian LiangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Chunyu JiangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Jiawen CuiCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Lan HongCollege of Medicine, Yanbian University, Yanji 133002, China.ORCID 0000-0003-1010-6039
Zhiyu HaoCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
You TangElectrical and Information Engineering College, Jilin Agricultural Science and Technology University, Jilin 132101, China.ORCID 0000-0002-6605-8497
Yuhao LiuCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.
Xun CuiCollege of Medicine, Yanbian University, Yanji 133002, China.
Xiaohua TengCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China.ORCID 0000-0003-0912-3325
Northeast Agricultural University · CNYanbian University · CNJilin Agricultural Science and Technology University · CN

Funding

key projects of science and technology development plan of Jilin province 20210204152YYScience and Technology Development Plan Project of Jilin Province YDZJ202201ZYTS692
6 · The paper itself

Abstract

Lead (Pb), a heavy metal environmental pollutant, poses a threat to the health of humans and birds. Inflammation is one of the most common pathological phenomena in the case of illness and poisoning. However, the underlying mechanisms of inflammation remain unclear. The cerebellum and the thalamus are important parts of the nervous system. To date, there have been no reports of Pb inducing inflammation in animal cerebellums or thalami. Selenium (Se) can relieve Pb poisoning. Therefore, we aimed to explore the mechanism by which Se alleviates Pb toxicity to the cerebellums and thalami of chickens by establishing a chicken Pb or/and Se treatment model. Our results demonstrated that exposure to Pb caused inflammatory damage in cerebellums and thalami, evidenced by the characteristics of inflammation, the decrease in anti-inflammatory factors (

Indexed as

inflammationleadoxidative stressseleniumselenoproteinsSPS2–GPx1–GSH–IL-2/IL-17–NO pathway

Identifiers

PMID38539903
PMCPMC10968013
OpenAlexW4392959653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.