Evidence map›Paper›PMID 38539900›Full record

ArticleAntioxidants (Basel, Switzerland)2024

TNFRSF1B Signaling Blockade Protects Airway Epithelial Cells from Oxidative Stress.

Javier Checa, Pau Fiol, Marta Guevara, Josep M Aran

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Wound repair and immune function in theFrontiers in cellular and infection microbiology · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Javier ChecaImmune-Inflammatory Processes and Gene Therapeutics Group, Genes, Disease and Therapy Program, Institut d'Investigació Biomèdica de Bellvitge-IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.
Pau FiolImmune-Inflammatory Processes and Gene Therapeutics Group, Genes, Disease and Therapy Program, Institut d'Investigació Biomèdica de Bellvitge-IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.
Marta GuevaraImmune-Inflammatory Processes and Gene Therapeutics Group, Genes, Disease and Therapy Program, Institut d'Investigació Biomèdica de Bellvitge-IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.
Josep M AranImmune-Inflammatory Processes and Gene Therapeutics Group, Genes, Disease and Therapy Program, Institut d'Investigació Biomèdica de Bellvitge-IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.ORCID 0000-0003-2827-9392
Institut d'Investigació Biomédica de Bellvitge · ES

Funding

Associació Catalana de Fibrosi QuísticaGovernment of Catalonia 2021SGR00521Government of Catalonia CERCA ProgrammeInstituto de Salud Carlos III PI16/00377Instituto de Salud Carlos III PI20/00464
6 · The paper itself

Abstract

Progressive respiratory airway destruction due to unresolved inflammation induced by periodic infectious exacerbation episodes is a hallmark of cystic fibrosis (CF) lung pathology. To clear bacteria, neutrophils release high amounts of reactive oxygen species (ROS), which inflict collateral damage to the neighboring epithelial cells causing oxidative stress. A former genome-wide small interfering RNA (siRNA) screening in CF submucosal gland cells, instrumental for mucociliary clearance, proposed tumor necrosis factor receptor superfamily member 1B (

Indexed as

airway epithelial cellscystic fibrosisoxidative stressRNAi knock-downTNFRSF1B

Identifiers

PMID38539900
PMCPMC10968085
OpenAlexW4392908814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.