ArticleAntioxidants (Basel, Switzerland)2024
DPPH Measurements and Structure-Activity Relationship Studies on the Antioxidant Capacity of Phenols.
Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
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- Encapsulation of Bee Pollen Phenolics with β-Cyclodextrin: Effects on Antioxidant Activity, Antimicrobial Properties, and Digestive Stability.Foods (Basel, Switzerland) · 2026Article
- Mechanistic profiling and optimized production of Altenusin, a fungal carboxy-biphenyl scaffold for tyrosinase inhibition.RSC advances · 2026Article
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- Chitosan Nanoparticles as a Biostimulant During In Vitro Multiplication of Vanilla Using Temporary Immersion Bioreactors.Molecules (Basel, Switzerland) · 2026Article
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5 authors.
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Abstract
The consumption of foods that are high in antioxidant capacity is believed to contribute to good health. Moreover, the addition of highly antioxidant compounds to foods is believed to prevent food deterioration. Among the known antioxidants in food, phenols have been identified as the primary antioxidants. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay is a simple, inexpensive, and rapid method widely used to evaluate the antioxidant capacity. Although the results of the DPPH assay depend on conditions such as the reaction time and concentration, the experimental conditions have not been standardized. Further, previous research that compared the antioxidant capacity determined through the DPPH assay largely focused on the differences in the specific substructures of approximately several dozen compounds. In this study, we conducted DPPH assays on 169 phenols under the same experimental conditions and summarized the correlation between their structures and activity. This DPPH assay study is the first single-laboratory investigation of the largest number of components in terms of their Trolox equivalent antioxidant capacities. Further, the analysis method was reproduced in an interlaboratory collaborative study, enabling its application in the reproduction and comparison of measurements in other laboratories.
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