ArticleAntioxidants (Basel, Switzerland)2024
Nanoencapsulation of Maqui (
Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Clinical Evidence on the Health Effects ofAntioxidants (Basel, Switzerland) · 2026Review
- Maqui as a Chilean Functional Food: Antioxidant Bioactivity, Nutritional Value, and Health Applications.Antioxidants (Basel, Switzerland) · 2026Review
- Preparation and property evaluation of oral colon targeted protein delivery system with sodium alginate and chitosan.Scientific reports · 2025Article
- Obtainment of Flavonoid-Enriched Fractions from Maqui (Antioxidants (Basel, Switzerland) · 2025Article
- Polymeric rumen-stable delivery systems for delivering nutricines.Open veterinary journal · 2025Review
- Optimization of Oil and Tocopherol Extraction from Maqui (Antioxidants (Basel, Switzerland) · 2024Article
- Nanoemulsions Based on Soluble Chenopodin/Alginate Complex for Colonic Delivery of Quercetin.Antioxidants (Basel, Switzerland) · 2024Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Maqui berries contain a high percentage of anthocyanins with high antioxidant and anti-inflammatory capacity but that are unstable in the colonic site. Nanocarriers based on polysaccharides and/or proteins can protect against the degradation of anthocyanins. The aim of this study was the nanoencapsulation of maqui extract (ME) in chitosan-tripolyphosphate (CTPP-ME), chenopodin (CH-ME), and chenopodin-alginate (CHA-ME). A standardised ME was prepared and then encapsulated in the nanosystems. The physicochemical properties, encapsulation parameters, and the interactions of ME with the nanovehicles were characterised. The cyanidin-3-glucoside released and ORAC activity in phosphate buffer at pH 7.4 were evaluated. The content of ME was 8-9 mg of cyanidin-3-glucoside/g of extract. CTPP with ME at 3% obtained the highest encapsulation efficiency (EE = 91%), and no significant differences were observed in size (274-362 nm), PDI (0.5-0.7), and zeta potential (+34-+41 mV) when the concentration of ME changed from 1% to 5%. CH-ME was shown to be smaller (152 nm) than CTPP-ME, and CH-ME and CHA-ME showed lower EE (79% and 54%, respectively) than CTPP-ME. FT-IR revealed a stronger interaction of ME with CTPP-ME than with CH-ME. Both systems showed a significantly lower release than free ME, and the T50 value of CTPP-ME 3% (328 min) was higher than CH-ME (197 min). Both protected the ORAC activity of ME.
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Registered trials
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