Evidence map›Paper›PMID 38539800›Full record

ReviewAntioxidants (Basel, Switzerland)2024

Crosstalk between Oxidative Stress and Inflammation Caused by Noise and Air Pollution-Implications for Neurodegenerative Diseases.

Marin Kuntić, Omar Hahad, Thomas Münzel, Andreas Daiber

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marin KuntićDepartment of Cardiology 1, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Omar HahadDepartment of Cardiology 1, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.ORCID 0000-0001-7823-7671
Thomas MünzelDepartment of Cardiology 1, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.ORCID 0000-0001-5503-4150
Andreas DaiberDepartment of Cardiology 1, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.ORCID 0000-0002-2769-0094
Johannes Gutenberg University Mainz · DE

Funding

European Cooperation in Science and Technology COST Action CA20121: Bench to bedside transition for pharmacological regulation of NRF2 in non-communicable diseases (BenBedPhar)German Centre for Cardiovascular Research Partner Site Rhine-Mainz - structural fundingStiftung Mainzer Herz "Noise & behavior"; "Shisha & CVD"Stiftung Rheinland-Pfalz für Innovation EXPOHEALTH - an environmental research network
6 · The paper itself

Abstract

Neurodegenerative diseases are often referred to as diseases of old age, and with the aging population, they are gaining scientific and medical interest. Environmental stressors, most notably traffic noise and air pollution, have recently come to the forefront, and have emerged as disease risk factors. The evidence for a connection between environmental risk factors and neurodegenerative disease is growing. In this review, the most common neurodegenerative diseases and their epidemiological association with traffic noise and air pollution are presented. Also, the most important mechanisms involved in neurodegenerative disease development, oxidative stress, and neuroinflammation are highlighted. An overview of the in vivo findings will provide a mechanistic link between noise, air pollution, and neurodegenerative pathology. Finally, the importance of the direct and indirect pathways, by which noise and air pollution cause cerebral damage, is discussed. More high-quality data are still needed from both epidemiological and basic science studies in order to better understand the causal connection between neurodegenerative diseases and environmental risk factors.

Indexed as

air pollutionenvironmental risk factorsinflammationneurodegenerationoxidative stresstransportation noise exposure

Identifiers

PMID38539800
PMCPMC10967531
OpenAlexW4392050753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.