Evidence map›Paper›PMID 38539671›Full record

ArticleBrain sciences2024

Immersive Virtual Reality for Treatment of Unilateral Spatial Neglect via Eye-Tracking Biofeedback: RCT Protocol and Usability Testing.

Alex Martino Cinnera, Valeria Verna, Matteo Marucci, Aurora Tavernese, Luisa Magnotti, Alessandro Matano, Chiara D'Acunto, Stefano Paolucci, Giovanni Morone, Viviana Betti and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06780488 (Visuo-Vestibular VR-based Stimulation Effects on Balance and Gait in Stroke Survivors), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06780488 narecruitingnot on this mapstarted 2025, after this paper: background citation

Visuo-Vestibular VR-based Stimulation Effects on Balance and Gait in Stroke Survivors

TypeinterventionalSponsorI.R.C.C.S. Fondazione Santa LuciaRan2025 to 2027Enrolled38ConditionsStrokeArmsReal Visual-Vestibuar Rehabilitation, Sham Rehabilitation
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Alex Martino CinneraIRCCS Santa Lucia Foundation, 00179 Rome, Italy.ORCID 0000-0001-7267-3253
Valeria VernaIRCCS Santa Lucia Foundation, 00179 Rome, Italy.ORCID 0000-0003-1000-7655
Matteo MarucciBraintrends Limited, Applied Neuroscience, 00192 Rome, Italy.ORCID 0000-0001-6431-9238
Aurora TaverneseIRCCS Santa Lucia Foundation, 00179 Rome, Italy.
Luisa MagnottiIRCCS Santa Lucia Foundation, 00179 Rome, Italy.
Alessandro MatanoIRCCS Santa Lucia Foundation, 00179 Rome, Italy.
Chiara D'AcuntoDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.
Stefano PaolucciIRCCS Santa Lucia Foundation, 00179 Rome, Italy.ORCID 0000-0002-3105-1148
Giovanni MoroneDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0003-3602-4197
Viviana BettiIRCCS Santa Lucia Foundation, 00179 Rome, Italy.ORCID 0000-0003-3429-2104
Marco TramontanoDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater University of Bologna, 40138 Bologna, Italy.ORCID 0000-0001-6034-0638
Fondazione Santa Lucia · ITSapienza University of Rome · ITAzienda USL di Bologna · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

About one-third of stroke survivors present unilateral spatial neglect (USN) that negatively impacts the rehabilitation outcome. We reported the study protocol and usability results of an eye-tracking (ET) biofeedback immersive virtual reality (iVR) protocol. Healthy controls and stroke patients with and without USN underwent a single session of the three iVR tasks. The system usability scale (SUS), adverse events (AEs), and ET data were collected and analyzed via parametric analysis. Twelve healthy controls (six young adults and six older adults) and seven patients with a diagnosis of single ischemic stroke (four without USN and three with confirmed diagnosis of USN) completed the usability investigation. SUS results showed good acceptability of the system for healthy controls and stroke patients without USN. ET results showed a lower performance for patients with USN concerning healthy controls and stroke patients without USN, in particular in the exploration of the left visual field. The results showed that the proposed iVR-ET biofeedback protocol is a safe and well-tolerated technique in patients with USN. The real-time feedback can induce a performance response supporting its investigation such as a treatment approach.

Indexed as

exergamingeye movementsneglectneurorehabilitationstroke rehabilitationvisual deficits

Identifiers

PMID38539671
PMCPMC10968842
OpenAlexW4392845531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.